Matches in SemOpenAlex for { <https://semopenalex.org/work/W1999223205> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W1999223205 endingPage "487" @default.
- W1999223205 startingPage "481" @default.
- W1999223205 abstract "Exposure of neuroblastoma cells (NBD-2) to 8-bromo-adenosine 3',5'-cyclic monophosphate (0.2-1.0 mM) (8-Br-cAMP) for 15 min caused a long term increase in the Vmax of tyrosine-3-monooxygenase activity (TH) beginning about 1 day after 8-Br-cAMP application. Cyclic AMP-dependent histone kinase was maximally activated in about 30 min and stayed activated above pretreatment levels for one hour. In cells exposed to 8-Br-cAMP for 15 min, separation of soluble and particle bound histone kinase showed that the total histone kinase activity in the soluble fraction decreased by 40%. This decrease was accompanied by an increase in protein kinase activity in the particulate fraction, suggesting enzyme translocation. After translocation, the enzyme appears to acquire a different substrate affinity because it prefers as a PO43- acceptor, acidic protein rather than histone. In NBD-2 cells this kinase appears to precede, and may be related to, the delayed increase in TH Vmax." @default.
- W1999223205 created "2016-06-24" @default.
- W1999223205 creator A5046011558 @default.
- W1999223205 creator A5051515082 @default.
- W1999223205 creator A5085817070 @default.
- W1999223205 date "1979-08-01" @default.
- W1999223205 modified "2023-09-23" @default.
- W1999223205 title "Translocation of cytosol protein kinase into nuclei and the induction of tyrosine hydroxylase in NBD-2 neuroblastoma cells" @default.
- W1999223205 cites W1542243713 @default.
- W1999223205 cites W156011056 @default.
- W1999223205 cites W1775749144 @default.
- W1999223205 cites W1965630284 @default.
- W1999223205 cites W2008660829 @default.
- W1999223205 cites W2009251383 @default.
- W1999223205 cites W2029225257 @default.
- W1999223205 cites W2045120757 @default.
- W1999223205 cites W2072904661 @default.
- W1999223205 cites W2109608980 @default.
- W1999223205 cites W2411529085 @default.
- W1999223205 cites W988868760 @default.
- W1999223205 doi "https://doi.org/10.1016/0006-8993(79)91052-7" @default.
- W1999223205 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/38881" @default.
- W1999223205 hasPublicationYear "1979" @default.
- W1999223205 type Work @default.
- W1999223205 sameAs 1999223205 @default.
- W1999223205 citedByCount "12" @default.
- W1999223205 crossrefType "journal-article" @default.
- W1999223205 hasAuthorship W1999223205A5046011558 @default.
- W1999223205 hasAuthorship W1999223205A5051515082 @default.
- W1999223205 hasAuthorship W1999223205A5085817070 @default.
- W1999223205 hasConcept C104317684 @default.
- W1999223205 hasConcept C138626823 @default.
- W1999223205 hasConcept C153911025 @default.
- W1999223205 hasConcept C159167319 @default.
- W1999223205 hasConcept C181199279 @default.
- W1999223205 hasConcept C184235292 @default.
- W1999223205 hasConcept C185592680 @default.
- W1999223205 hasConcept C2776991684 @default.
- W1999223205 hasConcept C42362537 @default.
- W1999223205 hasConcept C55493867 @default.
- W1999223205 hasConcept C62478195 @default.
- W1999223205 hasConcept C64927066 @default.
- W1999223205 hasConcept C86803240 @default.
- W1999223205 hasConcept C97029542 @default.
- W1999223205 hasConcept C98539663 @default.
- W1999223205 hasConceptScore W1999223205C104317684 @default.
- W1999223205 hasConceptScore W1999223205C138626823 @default.
- W1999223205 hasConceptScore W1999223205C153911025 @default.
- W1999223205 hasConceptScore W1999223205C159167319 @default.
- W1999223205 hasConceptScore W1999223205C181199279 @default.
- W1999223205 hasConceptScore W1999223205C184235292 @default.
- W1999223205 hasConceptScore W1999223205C185592680 @default.
- W1999223205 hasConceptScore W1999223205C2776991684 @default.
- W1999223205 hasConceptScore W1999223205C42362537 @default.
- W1999223205 hasConceptScore W1999223205C55493867 @default.
- W1999223205 hasConceptScore W1999223205C62478195 @default.
- W1999223205 hasConceptScore W1999223205C64927066 @default.
- W1999223205 hasConceptScore W1999223205C86803240 @default.
- W1999223205 hasConceptScore W1999223205C97029542 @default.
- W1999223205 hasConceptScore W1999223205C98539663 @default.
- W1999223205 hasIssue "3" @default.
- W1999223205 hasLocation W19992232051 @default.
- W1999223205 hasLocation W19992232052 @default.
- W1999223205 hasOpenAccess W1999223205 @default.
- W1999223205 hasPrimaryLocation W19992232051 @default.
- W1999223205 hasRelatedWork W1986393148 @default.
- W1999223205 hasRelatedWork W2004293894 @default.
- W1999223205 hasRelatedWork W2004754196 @default.
- W1999223205 hasRelatedWork W2009813704 @default.
- W1999223205 hasRelatedWork W2030492692 @default.
- W1999223205 hasRelatedWork W2041275422 @default.
- W1999223205 hasRelatedWork W2049661544 @default.
- W1999223205 hasRelatedWork W2104568994 @default.
- W1999223205 hasRelatedWork W2141791715 @default.
- W1999223205 hasRelatedWork W2020003695 @default.
- W1999223205 hasVolume "171" @default.
- W1999223205 isParatext "false" @default.
- W1999223205 isRetracted "false" @default.
- W1999223205 magId "1999223205" @default.
- W1999223205 workType "article" @default.