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- W1999228451 abstract "The immune surveillance hypothesis proposed over 50 years ago that many precancerous lesions are eliminated without a histological trace due to immunological pressure. Since then, it has become apparent that both the tumor and the anti-cancer immune response evolve over a long period to allow the eventual escape of nascent precancerous lesions into full-blown tumors. Although primarily focusing on loss of antigenicity, the immunoediting hypothesis has gradually evolved to appreciate the role of active immunosuppression in tumor progression, where myeloid leukocytes are increasingly recognized as the major driving force. This review highlights recent studies implicating how myeloid cells with antigen-presenting capabilities are co-opted by tumors to promote malignant progression. Because at least some advanced tumors remain significantly immunogenic, these new studies add a tweak to the immunoediting hypothesis as well as a rationale to block immunosuppressive mechanisms as a first-line intervention in cancer patients." @default.
- W1999228451 created "2016-06-24" @default.
- W1999228451 creator A5024136574 @default.
- W1999228451 creator A5047984384 @default.
- W1999228451 creator A5060460614 @default.
- W1999228451 date "2012-07-01" @default.
- W1999228451 modified "2023-09-26" @default.
- W1999228451 title "Anti-tumor immunity: Myeloid leukocytes control the immune landscape" @default.
- W1999228451 cites W1642873092 @default.
- W1999228451 cites W1653223339 @default.
- W1999228451 cites W1790309941 @default.
- W1999228451 cites W1964709968 @default.
- W1999228451 cites W1967229707 @default.
- W1999228451 cites W1981291019 @default.
- W1999228451 cites W1981400650 @default.
- W1999228451 cites W1982190534 @default.
- W1999228451 cites W1984803858 @default.
- W1999228451 cites W1993263603 @default.
- W1999228451 cites W2002157461 @default.
- W1999228451 cites W2004630197 @default.
- W1999228451 cites W2015207840 @default.
- W1999228451 cites W2019214729 @default.
- W1999228451 cites W2019541940 @default.
- W1999228451 cites W2028295154 @default.
- W1999228451 cites W2030908446 @default.
- W1999228451 cites W2044068003 @default.
- W1999228451 cites W2044199851 @default.
- W1999228451 cites W2044311801 @default.
- W1999228451 cites W2046505430 @default.
- W1999228451 cites W2046768931 @default.
- W1999228451 cites W2046972425 @default.
- W1999228451 cites W2050216284 @default.
- W1999228451 cites W2051582909 @default.
- W1999228451 cites W2052630690 @default.
- W1999228451 cites W2053353274 @default.
- W1999228451 cites W2053967595 @default.
- W1999228451 cites W2054936631 @default.
- W1999228451 cites W2058332988 @default.
- W1999228451 cites W2060672294 @default.
- W1999228451 cites W2062107951 @default.
- W1999228451 cites W2062889582 @default.
- W1999228451 cites W2063192133 @default.
- W1999228451 cites W2065968597 @default.
- W1999228451 cites W2070940280 @default.
- W1999228451 cites W2078197336 @default.
- W1999228451 cites W2082519303 @default.
- W1999228451 cites W2083872083 @default.
- W1999228451 cites W2093504658 @default.
- W1999228451 cites W2098005365 @default.
- W1999228451 cites W2105459360 @default.
- W1999228451 cites W2107079238 @default.
- W1999228451 cites W2109424201 @default.
- W1999228451 cites W2112744561 @default.
- W1999228451 cites W2114360891 @default.
- W1999228451 cites W2115586700 @default.
- W1999228451 cites W2117692326 @default.
- W1999228451 cites W2119896120 @default.
- W1999228451 cites W2120539661 @default.
- W1999228451 cites W2121626779 @default.
- W1999228451 cites W2121714000 @default.
- W1999228451 cites W2125533152 @default.
- W1999228451 cites W2126503106 @default.
- W1999228451 cites W2126593444 @default.
- W1999228451 cites W2130011407 @default.
- W1999228451 cites W2130201220 @default.
- W1999228451 cites W2133062667 @default.
- W1999228451 cites W2134905361 @default.
- W1999228451 cites W2135730659 @default.
- W1999228451 cites W2136798443 @default.
- W1999228451 cites W2137074525 @default.
- W1999228451 cites W2138397823 @default.
- W1999228451 cites W2138596774 @default.
- W1999228451 cites W2139870920 @default.
- W1999228451 cites W2142300779 @default.
- W1999228451 cites W2150330457 @default.
- W1999228451 cites W2150678612 @default.
- W1999228451 cites W2150781849 @default.
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- W1999228451 cites W2155360682 @default.
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- W1999228451 cites W2160390319 @default.
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- W1999228451 cites W2167550136 @default.
- W1999228451 cites W2171524340 @default.
- W1999228451 cites W2172170289 @default.
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- W1999228451 doi "https://doi.org/10.1016/j.cellimm.2012.06.014" @default.
- W1999228451 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3490130" @default.
- W1999228451 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23121972" @default.
- W1999228451 hasPublicationYear "2012" @default.
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