FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1999233489> ?p ?o ?g. }

• W1999233489 endingPage "628" @default.
• W1999233489 startingPage "619" @default.
• W1999233489 abstract "Dipteran insects, like mosquitoes, possess more than two prophenoloxidase (PPO) genes, but it is unclear whether their gene products differ in biochemical properties and physiological functions. Here, we used three Drosophila melanogaster PPOs as models to study their properties through expression in S2 cells. Our data revealed that the PPOs were expressed in the ethanol-activatable conformation: rPPO1 and rPPO2 needed additional Cu2+ in the medium, but rPPO3 did not. rPPO1 bound Cu2+ within minutes; rPPO2 did that in hours when Cu2+ were present at a higher concentration. Thus, rPPO1 and rPPO2 were expressed as apo-rPPO and became holo-PPO upon Cu2+ binding; rPPO3 was holo-PPO immediately after expression. Surprisingly, in the absence of ethanol, the apparently intact rPPO3 catalyzed dopamine oxidation and melanization. The successful method for rPPO expression in S2 cells described in this paper will provide us with an opportunity to study the properties of a specific PPO gene in a small insect like mosquitoes in the future." @default.
• W1999233489 created "2016-06-24" @default.
• W1999233489 creator A5011741256 @default.
• W1999233489 creator A5014662537 @default.
• W1999233489 creator A5015736102 @default.
• W1999233489 creator A5016485135 @default.
• W1999233489 creator A5023719427 @default.
• W1999233489 creator A5040795581 @default.
• W1999233489 creator A5048279362 @default.
• W1999233489 creator A5048564689 @default.
• W1999233489 creator A5059675805 @default.
• W1999233489 creator A5077722406 @default.
• W1999233489 creator A5078033151 @default.
• W1999233489 creator A5087278256 @default.
• W1999233489 date "2012-03-01" @default.
• W1999233489 modified "2023-09-22" @default.
• W1999233489 title "Drosophila melanogaster prophenoloxidases respond inconsistently to Cu2+ and have different activity in vitro" @default.
• W1999233489 cites W133779161 @default.
• W1999233489 cites W1410830647 @default.
• W1999233489 cites W1565460474 @default.
• W1999233489 cites W1964047219 @default.
• W1999233489 cites W1969157447 @default.
• W1999233489 cites W1981440814 @default.
• W1999233489 cites W1989820028 @default.
• W1999233489 cites W2008808342 @default.
• W1999233489 cites W2015446823 @default.
• W1999233489 cites W2018210931 @default.
• W1999233489 cites W2021849213 @default.
• W1999233489 cites W2033906596 @default.
• W1999233489 cites W2035891906 @default.
• W1999233489 cites W2036302840 @default.
• W1999233489 cites W2040007543 @default.
• W1999233489 cites W2055490715 @default.
• W1999233489 cites W2067744084 @default.
• W1999233489 cites W2090645903 @default.
• W1999233489 cites W2102517829 @default.
• W1999233489 cites W2105663335 @default.
• W1999233489 cites W2158091936 @default.
• W1999233489 cites W263115363 @default.
• W1999233489 cites W4239368937 @default.
• W1999233489 doi "https://doi.org/10.1016/j.dci.2011.12.001" @default.
• W1999233489 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22178920" @default.
• W1999233489 hasPublicationYear "2012" @default.
• W1999233489 type Work @default.
• W1999233489 sameAs 1999233489 @default.
• W1999233489 citedByCount "20" @default.
• W1999233489 countsByYear W19992334892012 @default.
• W1999233489 countsByYear W19992334892013 @default.
• W1999233489 countsByYear W19992334892014 @default.
• W1999233489 countsByYear W19992334892017 @default.
• W1999233489 countsByYear W19992334892018 @default.
• W1999233489 countsByYear W19992334892020 @default.
• W1999233489 countsByYear W19992334892021 @default.
• W1999233489 countsByYear W19992334892022 @default.
• W1999233489 crossrefType "journal-article" @default.
• W1999233489 hasAuthorship W1999233489A5011741256 @default.
• W1999233489 hasAuthorship W1999233489A5014662537 @default.
• W1999233489 hasAuthorship W1999233489A5015736102 @default.
• W1999233489 hasAuthorship W1999233489A5016485135 @default.
• W1999233489 hasAuthorship W1999233489A5023719427 @default.
• W1999233489 hasAuthorship W1999233489A5040795581 @default.
• W1999233489 hasAuthorship W1999233489A5048279362 @default.
• W1999233489 hasAuthorship W1999233489A5048564689 @default.
• W1999233489 hasAuthorship W1999233489A5059675805 @default.
• W1999233489 hasAuthorship W1999233489A5077722406 @default.
• W1999233489 hasAuthorship W1999233489A5078033151 @default.
• W1999233489 hasAuthorship W1999233489A5087278256 @default.
• W1999233489 hasConcept C104317684 @default.
• W1999233489 hasConcept C136449434 @default.
• W1999233489 hasConcept C150194340 @default.
• W1999233489 hasConcept C202751555 @default.
• W1999233489 hasConcept C2776041557 @default.
• W1999233489 hasConcept C2776998849 @default.
• W1999233489 hasConcept C2777379243 @default.
• W1999233489 hasConcept C2777612826 @default.
• W1999233489 hasConcept C2780104201 @default.
• W1999233489 hasConcept C2780161600 @default.
• W1999233489 hasConcept C2781271842 @default.
• W1999233489 hasConcept C54355233 @default.
• W1999233489 hasConcept C55493867 @default.
• W1999233489 hasConcept C59822182 @default.
• W1999233489 hasConcept C86803240 @default.
• W1999233489 hasConcept C8891405 @default.
• W1999233489 hasConcept C95444343 @default.
• W1999233489 hasConceptScore W1999233489C104317684 @default.
• W1999233489 hasConceptScore W1999233489C136449434 @default.
• W1999233489 hasConceptScore W1999233489C150194340 @default.
• W1999233489 hasConceptScore W1999233489C202751555 @default.
• W1999233489 hasConceptScore W1999233489C2776041557 @default.
• W1999233489 hasConceptScore W1999233489C2776998849 @default.
• W1999233489 hasConceptScore W1999233489C2777379243 @default.
• W1999233489 hasConceptScore W1999233489C2777612826 @default.
• W1999233489 hasConceptScore W1999233489C2780104201 @default.
• W1999233489 hasConceptScore W1999233489C2780161600 @default.
• W1999233489 hasConceptScore W1999233489C2781271842 @default.
• W1999233489 hasConceptScore W1999233489C54355233 @default.
• W1999233489 hasConceptScore W1999233489C55493867 @default.
• W1999233489 hasConceptScore W1999233489C59822182 @default.

• next