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- W1999233490 abstract "—1The brains of 17-day-old quaking and jimpy mice were compared with those of the corresponding normal phenotypes. The concentrations of cerebroside and sulphatide were found to be markedly lower in the affected mutants, while the relative amounts of ceramide and free fatty acid appeared normal.2The concentration of cerebroside glactosidase was not significantly abnormal in the jimpy mice but was about 17 per cent lower in quaking mice. In contrast, the relative amount of the enzyme that could be dispersed by sonication was considerably higher in the jimpy animals. It is suggested that this increase is a causative factor in the aetiology of the latter disease.3The concentrations of other acid hydrolases were determined, as well as the relative amounts dispersible by sonication. No difference was seen between the phenotypes with NPGalH, NPGluH, and nitrocatechol sulphate hydrolase.4An improved solvent system for the TLC detection of ceramide in brain lipids is described." @default.
- W1999233490 created "2016-06-24" @default.
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- W1999233490 date "1969-03-01" @default.
- W1999233490 modified "2023-09-24" @default.
- W1999233490 title "HYDROLASE ACTIVITIES IN BRAIN OF NEUROLOGICAL MUTANTS: CEREBROSIDE GALACTOSIDASE, NITROPHENYL GALACTOSIDE HYDROLASE, NITROPHENYL LUCOSIDE HYDROLASE AND SULPHATASE" @default.
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- W1999233490 doi "https://doi.org/10.1111/j.1471-4159.1969.tb10386.x" @default.
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