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- W1999291269 abstract "Plasma estradiol before and after administration of LH-RH/FSH-RH in females with varying duration of secondary amenorrhea was measured. 12 patients with amenorrhea of more than 6 months duration were studied. In 9 of the 12 patients plasma estradiol showed a 2 to 3-fold rise abov e the mean basal level by 6 hours after a single iv injection of synthetic LH-RH/FSH-RH. 2 of the remaining 3 patients had persistently high basal plasma gonadotropins in keeping with a diagnosis of premature menopause. 1 patient had secondary amenorrhea of 7 years duration. The consistent rise of plasma estradiol above baseline by 6 hours after iv administration of LH-RH/FSH-RH and the relatively short duration of the plasma estradiol assay (5 hours) suggest that this assay may be preferable to gonadotropin assays as the end point of the LH-RH/FSH-RH test in females. If a less than 2-fold increase in plasma estradiol is found pituitary reserve can be more intensively studied by assaying plasma FSH and LH." @default.
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- W1999291269 date "1974-10-01" @default.
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- W1999291269 title "PLASMA OESTRADIOL RESPONSE TO SYNTHETIC FOLLICLE STIMULATING HORMONE/LUTEINIZING HORMONE RELEASING HORMONE IN PATIENTS WITH SECONDARY AMENORRHOEA" @default.
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- W1999291269 doi "https://doi.org/10.1111/j.1471-0528.1974.tb00382.x" @default.
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