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• W1999342334 endingPage "79" @default.
• W1999342334 startingPage "71" @default.
• W1999342334 abstract "Progesterone plays an important, if not controversial, role in mammary epithelial cell proliferation and differentiation. Evidence supports that progesterone promotes rodent mammary carcinogenesis under some conditions, progesterone receptors (PR) are necessary for murine mammary gland tumorigenesis, and exogenous progestin use in post-menopausal women increases breast cancer risk. Thus, the progesterone/PR signaling axis can promote mammary tumorigenesis, albeit in a context-dependent manner. A mechanistic basis for the tumor promoting actions of progesterone has thus far remained unknown. Recent studies, however, have identified a novel role for progesterone in controlling the number and function of stem and progenitor cell populations in the normal human and mouse mammary glands, and in human breast cancers. These discoveries promise to reshape our perception of progesterone function in the mammary gland, and have spawned new hypotheses for how progestins may increase the risk of breast cancer. Here we review studies on progesterone regulation of mammary stem cells in normal and malignant tissue, and their implications for breast cancer risk, tumorigenesis, and tumor behavior." @default.
• W1999342334 created "2016-06-24" @default.
• W1999342334 creator A5001957077 @default.
• W1999342334 creator A5068959723 @default.
• W1999342334 date "2012-06-01" @default.
• W1999342334 modified "2023-09-24" @default.
• W1999342334 title "Progesterone regulation of stem and progenitor cells in normal and malignant breast" @default.
• W1999342334 cites W1495654654 @default.
• W1999342334 cites W1536810585 @default.
• W1999342334 cites W1588517436 @default.
• W1999342334 cites W1850198354 @default.
• W1999342334 cites W1867169935 @default.
• W1999342334 cites W1965880390 @default.
• W1999342334 cites W1970078194 @default.
• W1999342334 cites W1970822594 @default.
• W1999342334 cites W1971949613 @default.
• W1999342334 cites W1979440527 @default.
• W1999342334 cites W1982798298 @default.
• W1999342334 cites W1983876698 @default.
• W1999342334 cites W1984433201 @default.
• W1999342334 cites W1987417875 @default.
• W1999342334 cites W1989458228 @default.
• W1999342334 cites W1991527725 @default.
• W1999342334 cites W1991555835 @default.
• W1999342334 cites W1992146811 @default.
• W1999342334 cites W1992505028 @default.
• W1999342334 cites W1999536395 @default.
• W1999342334 cites W2000664436 @default.
• W1999342334 cites W2000877684 @default.
• W1999342334 cites W2001144553 @default.
• W1999342334 cites W2007624933 @default.
• W1999342334 cites W2010867675 @default.
• W1999342334 cites W2011612270 @default.
• W1999342334 cites W2016999459 @default.
• W1999342334 cites W2017107870 @default.
• W1999342334 cites W2022297771 @default.
• W1999342334 cites W2023316892 @default.
• W1999342334 cites W2023398724 @default.
• W1999342334 cites W2023427658 @default.
• W1999342334 cites W2030204392 @default.
• W1999342334 cites W2030899358 @default.
• W1999342334 cites W2032685601 @default.
• W1999342334 cites W2036638605 @default.
• W1999342334 cites W2040162597 @default.
• W1999342334 cites W2043725619 @default.
• W1999342334 cites W2045376146 @default.
• W1999342334 cites W2045696513 @default.
• W1999342334 cites W2050219190 @default.
• W1999342334 cites W2051255001 @default.
• W1999342334 cites W2051783431 @default.
• W1999342334 cites W2055498399 @default.
• W1999342334 cites W2056294267 @default.
• W1999342334 cites W2057292695 @default.
• W1999342334 cites W2061975024 @default.
• W1999342334 cites W2064616338 @default.
• W1999342334 cites W2068109871 @default.
• W1999342334 cites W2070430161 @default.
• W1999342334 cites W2093283052 @default.
• W1999342334 cites W2093903677 @default.
• W1999342334 cites W2094833794 @default.
• W1999342334 cites W2095320189 @default.
• W1999342334 cites W2095671568 @default.
• W1999342334 cites W2097255042 @default.
• W1999342334 cites W2102596641 @default.
• W1999342334 cites W2109221809 @default.
• W1999342334 cites W2115210458 @default.
• W1999342334 cites W2115504447 @default.
• W1999342334 cites W2117963341 @default.
• W1999342334 cites W2124383610 @default.
• W1999342334 cites W2125471242 @default.
• W1999342334 cites W2126811493 @default.
• W1999342334 cites W2127617517 @default.
• W1999342334 cites W2133108176 @default.
• W1999342334 cites W2133341870 @default.
• W1999342334 cites W2137162822 @default.
• W1999342334 cites W2139272277 @default.
• W1999342334 cites W2141358477 @default.
• W1999342334 cites W2142709970 @default.
• W1999342334 cites W2146074268 @default.
• W1999342334 cites W2148131050 @default.
• W1999342334 cites W2149120477 @default.
• W1999342334 cites W2151138778 @default.
• W1999342334 cites W2151948621 @default.
• W1999342334 cites W2153864725 @default.
• W1999342334 cites W2156624320 @default.
• W1999342334 cites W2159610509 @default.
• W1999342334 cites W2161030313 @default.
• W1999342334 cites W2169191111 @default.
• W1999342334 cites W2411761847 @default.
• W1999342334 cites W3162684029 @default.
• W1999342334 cites W4229730268 @default.
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• W1999342334 doi "https://doi.org/10.1016/j.mce.2011.09.021" @default.
• W1999342334 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3288619" @default.
• W1999342334 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21945473" @default.
• W1999342334 hasPublicationYear "2012" @default.
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