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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1999362215> ?p ?o ?g. }

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• W1999362215 abstract "Glucocorticoid receptor of lactating mouse mammary gland cytosol was exposed to heparin when the receptor was either steroid-free or steroid-bound. Heparin caused a dose-dependent and time-dependent loss of steroid binding activity (inactivation) of the steroid-free receptor; this heparin-induced inactivation was inhibited by molybdate. In contrast, steroid-bound receptor maintained its steroid binding capacity in the presence of heparin but the heparin caused transformation of receptor as detected by increased binding to DNA-cellulose and ATP-Sepharose. Heparin also converted steroid-bound receptor from the 7-8S form to the 4S form. Molybdate inhibited both the heparin-induced transformation and associated conversion to the 4S form." @default.
• W1999362215 created "2016-06-24" @default.
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• W1999362215 date "1984-06-01" @default.
• W1999362215 modified "2023-09-26" @default.
• W1999362215 title "Heparin-mediated inactivation and transformation of mammary cytoplasmic glucocorticoid receptor" @default.
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• W1999362215 doi "https://doi.org/10.1016/0022-4731(84)90147-x" @default.
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