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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1999439810> ?p ?o ?g. }

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• W1999439810 abstract "System xc- mediates transport of cystine and glutamate across the mammalian plasma membrane in a Na(+)-independent manner. This transport activity can be induced in mouse peritoneal macrophages during culture by diethylmaleate, a sulfhydryl-reactive agent. We injected mRNA from such macrophages into Xenopus oocytes and demonstrated the expression of System xc-, i.e., a Na(+)-independent, glutamate-inhibitable cysteine transport system. The expressed cystine transport activity depended on the assay temperature, in that cystine uptake measured at 37 degrees C was severalfold higher than that measured at 20 degrees C. Injection of size-fractionated mRNA indicated that the System xc- transporter of the mouse macrophage is encoded by mRNA of 1.5 to 2.9 kb." @default.
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• W1999439810 date "1991-08-01" @default.
• W1999439810 modified "2023-10-15" @default.
• W1999439810 title "Expression of the mouse macrophage cystine transporter in Xenopus laevis oocytes" @default.
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• W1999439810 doi "https://doi.org/10.1016/0003-9861(91)90443-m" @default.
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