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- W1999457029 endingPage "985" @default.
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- W1999457029 abstract "Metastatic mouse melanoma cells have a high affinity for the basement membrane and the ability to degrade it; these properties may allow tumor cells to invade the membrane and disseminate. In this study it was found that the metastatic potential of mouse melanoma cells varied when the cells were exposed in culture to fibronectin or laminin. After removal of fibronectin or exposure to laminin, the cells had an increased affinity for basement membrane collagen, were more invasive of basement membranes in vitro, and produced more lung colonies in vivo. These changes are correlated with and may be due to an increase in the laminin-binding capacity of the tumor cell surface." @default.
- W1999457029 created "2016-06-24" @default.
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- W1999457029 date "1984-11-23" @default.
- W1999457029 modified "2023-09-24" @default.
- W1999457029 title "Modulation of the Metastatic Activity of Melanoma Cells by Laminin and Fibronectin" @default.
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- W1999457029 doi "https://doi.org/10.1126/science.6505678" @default.
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