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- W1999461850 abstract "Prior to the advent of fetal ultrasound, multicystic dysplastic kidney (MCDK), defined as a unilateral grossly dysplastic organ with little or no function in which cystic elements predominate, was the most common abdominal, usually flank, mass detected in the neonate by physical examination. Historically, nephrectomy was usually performed in late infancy 1 The incidence was approximately 1 in 4300 live births. 2 The security with which diagnosis can be made--from the characteristic appearance on ultrasound plus nonfunction on renal scan--and the relatively few late complications of MCDK have led to the suggestion that such patients should be managed with surveillance instead of by nephrectomy. 1'3 We review the indications for surgical management of MCDK and focus on the incidence of hypertension in MCDK, which is presently underestimated. Successful cyst aspiration for the rare case of respiratory embarrassment has been reported. 4 Indications for nephrectomy include uncertain diagnosis, pain, urinary tract infection or abscess, malignancy, and hypertension. 3 Specifically, Ambrose 5 reported on 27 adults requiring surgery for pain or infection. Furthermore, 7 cases of malignancy in association with MCDK have been reported since 1957, including 4 cases in children: 2 Wilms' tumors, 1 adenosarcoma, and 1 renal cell carcinoma. 1 Of the 508 patients now entered in the National Multicystic Kidney Registry, misdiagnosis occurred in 6 of the first i 8 i operated cases, but the hydronephrosis was so severe the kidneys were not salvageable, a,6 Thirteen patients in the Registry have had urinary tract infections, and 2 patients had hematuria. One of the patients had pain, but no tumors were reported." @default.
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- W1999461850 date "1994-09-01" @default.
- W1999461850 modified "2023-10-14" @default.
- W1999461850 title "The risk of hypertension is underestimated in the multicystic dysplastic kidney: A personal perspective" @default.
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- W1999461850 doi "https://doi.org/10.1016/s0090-4295(94)80102-9" @default.
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