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• W1999463030 abstract "Two strains of mice (NMRI and C57/BL) were each immunized with a 15kDa recombinant Fasciola hepatica fatty acid binding protein (FABP) (Fh15) and challenged percutaneously with Schistosoma bovis cercariae. C57/BL mice immunized with Fh15 had significant reductions in S. bovis worm burden recoveries (72% reductions over controls). When using NMRI mice, Fh15 in Freund's adjuvant failed to induce significant protection against S. bovis. In C57/BL mice, only antibodies to the IgG2a isotype increased after the second immunization and remained high through 8 weeks of S. bovis infection. This is the first time that a heterologous recombinant molecule from F. hepatica has been used in vaccination against S. bovis, obtaining a significant reduction in the number of worms in C57/BL mice." @default.
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• W1999463030 date "2000-07-01" @default.
• W1999463030 modified "2023-10-18" @default.
• W1999463030 title "Vaccination of mice against Schistosoma bovis with a recombinant fatty acid binding protein from Fasciola hepatica" @default.
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• W1999463030 doi "https://doi.org/10.1016/s0304-4017(00)00263-6" @default.
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