FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1999467062> ?p ?o ?g. }

• W1999467062 endingPage "805" @default.
• W1999467062 startingPage "801" @default.
• W1999467062 abstract "Type 1 iodothyronine deiodinase (D1) converts thyroxin (T4) into tri-iodothyronine (T3). Strong evidence indicates that thyroid hormone metabolism is disturbed in neoplasms such as thyroid and breast cancer. However, there is limited data concerning the function of the D1 enzyme in liver tumors. We aimed to estimate the enzymatic activity of D1 in two different common liver tumors.We obtained 20 tumor samples from patients who had undergone a liver resection. Of the tissue samples, there were 13 benign lesions of focal nodular hyperplasia (FNH) and 7 malignant lesions of hepatocellular carcinomas (HCC). The D1 activity was assessed by measuring the amount of radioactive iodine released in reaction to D1-catalysed deiodination. Groups were compared by the Mann-Whitney non-parametrical test for independent trials, and the Kruskal Wallis test.The enzymatic activity of D1 was not significantly altered in the FNH group (median = 536 fmol/mg of protein/min; p = 0.972) and HCC group (367 fmol/mg; p = 0.128) when compared to matched normal liver parenchyma controls (546 fmol/mg and 556 fmol/mg, respectively).Liver parenchyma expresses high levels of D1. The results clearly revealed that D1 activity was not significantly different between benign and malignant tumors (FNH and HCC) compared to healthy liver parenchyma cells." @default.
• W1999467062 created "2016-06-24" @default.
• W1999467062 creator A5008130280 @default.
• W1999467062 creator A5038408218 @default.
• W1999467062 creator A5052405518 @default.
• W1999467062 creator A5068956244 @default.
• W1999467062 creator A5079491798 @default.
• W1999467062 creator A5079737556 @default.
• W1999467062 creator A5082438802 @default.
• W1999467062 creator A5087124519 @default.
• W1999467062 date "2014-01-01" @default.
• W1999467062 modified "2023-10-15" @default.
• W1999467062 title "Enzymatic activity of type 1 iodothyronine deiodinase in selected liver tumors" @default.
• W1999467062 cites W1617638472 @default.
• W1999467062 cites W1968302765 @default.
• W1999467062 cites W1986537187 @default.
• W1999467062 cites W1989781457 @default.
• W1999467062 cites W1989918094 @default.
• W1999467062 cites W1990785028 @default.
• W1999467062 cites W1993080614 @default.
• W1999467062 cites W2001564798 @default.
• W1999467062 cites W2003050029 @default.
• W1999467062 cites W2006140668 @default.
• W1999467062 cites W2009279040 @default.
• W1999467062 cites W2018227401 @default.
• W1999467062 cites W2034244313 @default.
• W1999467062 cites W2041353175 @default.
• W1999467062 cites W2059988795 @default.
• W1999467062 cites W2064544204 @default.
• W1999467062 cites W2077897761 @default.
• W1999467062 cites W2081070032 @default.
• W1999467062 cites W2082935047 @default.
• W1999467062 cites W2084429552 @default.
• W1999467062 cites W2099216906 @default.
• W1999467062 cites W2103637700 @default.
• W1999467062 cites W2104878795 @default.
• W1999467062 cites W2118160391 @default.
• W1999467062 cites W2121276418 @default.
• W1999467062 cites W2132086750 @default.
• W1999467062 cites W2152847902 @default.
• W1999467062 cites W2400453483 @default.
• W1999467062 doi "https://doi.org/10.5114/aoms.2013.34323" @default.
• W1999467062 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4175756" @default.
• W1999467062 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25276167" @default.
• W1999467062 hasPublicationYear "2014" @default.
• W1999467062 type Work @default.
• W1999467062 sameAs 1999467062 @default.
• W1999467062 citedByCount "6" @default.
• W1999467062 countsByYear W19994670622016 @default.
• W1999467062 countsByYear W19994670622017 @default.
• W1999467062 countsByYear W19994670622018 @default.
• W1999467062 countsByYear W19994670622023 @default.
• W1999467062 crossrefType "journal-article" @default.
• W1999467062 hasAuthorship W1999467062A5008130280 @default.
• W1999467062 hasAuthorship W1999467062A5038408218 @default.
• W1999467062 hasAuthorship W1999467062A5052405518 @default.
• W1999467062 hasAuthorship W1999467062A5068956244 @default.
• W1999467062 hasAuthorship W1999467062A5079491798 @default.
• W1999467062 hasAuthorship W1999467062A5079737556 @default.
• W1999467062 hasAuthorship W1999467062A5082438802 @default.
• W1999467062 hasAuthorship W1999467062A5087124519 @default.
• W1999467062 hasBestOaLocation W19994670621 @default.
• W1999467062 hasConcept C126322002 @default.
• W1999467062 hasConcept C134018914 @default.
• W1999467062 hasConcept C142724271 @default.
• W1999467062 hasConcept C181199279 @default.
• W1999467062 hasConcept C196822366 @default.
• W1999467062 hasConcept C2776515397 @default.
• W1999467062 hasConcept C2778019345 @default.
• W1999467062 hasConcept C2778288131 @default.
• W1999467062 hasConcept C2778417266 @default.
• W1999467062 hasConcept C2778721783 @default.
• W1999467062 hasConcept C526584372 @default.
• W1999467062 hasConcept C55493867 @default.
• W1999467062 hasConcept C71315377 @default.
• W1999467062 hasConcept C71924100 @default.
• W1999467062 hasConcept C86803240 @default.
• W1999467062 hasConceptScore W1999467062C126322002 @default.
• W1999467062 hasConceptScore W1999467062C134018914 @default.
• W1999467062 hasConceptScore W1999467062C142724271 @default.
• W1999467062 hasConceptScore W1999467062C181199279 @default.
• W1999467062 hasConceptScore W1999467062C196822366 @default.
• W1999467062 hasConceptScore W1999467062C2776515397 @default.
• W1999467062 hasConceptScore W1999467062C2778019345 @default.
• W1999467062 hasConceptScore W1999467062C2778288131 @default.
• W1999467062 hasConceptScore W1999467062C2778417266 @default.
• W1999467062 hasConceptScore W1999467062C2778721783 @default.
• W1999467062 hasConceptScore W1999467062C526584372 @default.
• W1999467062 hasConceptScore W1999467062C55493867 @default.
• W1999467062 hasConceptScore W1999467062C71315377 @default.
• W1999467062 hasConceptScore W1999467062C71924100 @default.
• W1999467062 hasConceptScore W1999467062C86803240 @default.
• W1999467062 hasLocation W19994670621 @default.
• W1999467062 hasLocation W19994670622 @default.
• W1999467062 hasLocation W19994670623 @default.
• W1999467062 hasLocation W19994670624 @default.
• W1999467062 hasOpenAccess W1999467062 @default.
• W1999467062 hasPrimaryLocation W19994670621 @default.

• next