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• W1999482904 abstract "idea the authors had that a simplification of this computation to speed up the measuring process could have an impact on the clinical scenario. Their solution is based on the analysis of a limited number of MR images to approximate kidney and cyst volumes. To this regard, we strongly believe that using image processing techniques to drastically reduce processing time and fully exploit the information contained in the acquired dataset without applying any geometrical approximation and provide reliable volume estimates could be helpful for the computation of the parameters CRISP proved to be clinically important. The availability of good quality MR images, refined image processing algorithms and computational power makes this option completely feasible. Indeed, some works proposing semiautomated or highly automated methods to quantify total kidney volumes in autosomal dominant polycystic kidney disease patients without using geometrical modeling and approximations have been published [2–4] . In particular, in a work that some of us coauthored [3] , an extremely strong correlation (r = 0.99) was found between an automated measurement (requiring about We recently read and appreciated the paper ‘Novel approach to estimate kidney and cyst volumes using mid-slice magnetic resonance images in polycystic kidney disease’ by Bae et al. [1] . The paper is very interesting and we recognize the intensive and very useful work the Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease (CRISP) has conducted in the last years on this topic to develop methods to define a surrogate marker of the disease. Indeed, one of the most relevant results of CRISP was the evidence that magnetic resonance (MR) imaging is the best procedure for estimating changes in renal and cystic volume in autosomal dominant polycystic kidney disease over short followup periods. As stated in the study [1] , assessment of total renal and cystic volume is usually computed by manually tracing renal or cyst contours in a set of contiguous MR images and by summing the products of the area measurements and the slice thickness. We completely agree with the authors that measuring the area of every slice in such amounts of images is laborious, time-consuming and not applicable in routine clinical practice. For this reason we share the Published online: February 11, 2014" @default.
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• W1999482904 date "2014-01-01" @default.
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• W1999482904 title "Comment on the Paper: ‘Novel Approach to Estimate Kidney and Cyst Volumes Using Mid-Slice Magnetic Resonance Images in Polycystic Kidney Disease'" @default.
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• W1999482904 doi "https://doi.org/10.1159/000358911" @default.
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