FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1999536411> ?p ?o ?g. }

• W1999536411 endingPage "69" @default.
• W1999536411 startingPage "61" @default.
• W1999536411 abstract "The drug discrimination paradigm was used to evaluate the role of certain ligand-gated ion channels in the discriminative stimulus properties of ethanol. Rats were trained to discriminate ethanol (1.0 g/kg) from saline vehicle under the FR10 schedule of sweetened milk reinforcement. The discrimination of lower ethanol doses was enhanced by either the GABA(A) receptor positive modulator, diazepam (0.5 mg/kg), or nicotinic acetylcholine receptor agonist, nicotine (0.3 mg/kg). Neither diazepam nor nicotine produced any effect on the rate of responding. Both the NMDA receptor competitive antagonist, CGP 40116 (0.5 mg/kg) and the 5-HT) receptor agonist, 1-(m-chlorophenyl)-biguanide (5.0 mg/kg) enhanced the cueing properties of lower ethanol doses, but these effects were associated with a significant reduction in the response rate. The ethanol-like stimulus effects produced by diazepam or CGP 40116 were not influenced by 0.3 mg/kg nicotine. In contrast, CGP 40116 moderately enhanced the ethanol-like stimulus effects of diazepam. The present results show that: 1) pretreatment with nicotine, diazepam, CGP 40116 or 1-(m-chlorophenyl)-biguanide enhance the ethanol discrimination; 2) neither the GABA(A) nor the NMDA receptor complex alone is critically involved in the nicotine-induced enhancement of the ethanol discrimination; 3) NMDA receptor competitive antagonist and GABAergic benzodiazepine derivative may produce moderate additive effects in rats trained to discriminate ethanol." @default.
• W1999536411 created "2016-06-24" @default.
• W1999536411 creator A5045544787 @default.
• W1999536411 creator A5058864296 @default.
• W1999536411 date "1998-05-01" @default.
• W1999536411 modified "2023-10-14" @default.
• W1999536411 title "Discrimination of Ethanol in Rats: Effects of Nicotine, Diazepam, CGP 40116, and 1-(m-Chlorophenyl)-biguanide" @default.
• W1999536411 cites W1588587238 @default.
• W1999536411 cites W1964325567 @default.
• W1999536411 cites W1972667140 @default.
• W1999536411 cites W1982282592 @default.
• W1999536411 cites W1984228586 @default.
• W1999536411 cites W1988109427 @default.
• W1999536411 cites W1990547340 @default.
• W1999536411 cites W1991544416 @default.
• W1999536411 cites W1994093302 @default.
• W1999536411 cites W1998001722 @default.
• W1999536411 cites W1998757791 @default.
• W1999536411 cites W1998924641 @default.
• W1999536411 cites W2002489800 @default.
• W1999536411 cites W2004984114 @default.
• W1999536411 cites W2006269841 @default.
• W1999536411 cites W2007188824 @default.
• W1999536411 cites W2017624584 @default.
• W1999536411 cites W2022047391 @default.
• W1999536411 cites W2024681271 @default.
• W1999536411 cites W2027627802 @default.
• W1999536411 cites W2030113707 @default.
• W1999536411 cites W2031423152 @default.
• W1999536411 cites W2035974852 @default.
• W1999536411 cites W2036707931 @default.
• W1999536411 cites W2037253922 @default.
• W1999536411 cites W2042134449 @default.
• W1999536411 cites W2042510291 @default.
• W1999536411 cites W2043205042 @default.
• W1999536411 cites W2051606745 @default.
• W1999536411 cites W2054168593 @default.
• W1999536411 cites W2071122099 @default.
• W1999536411 cites W2073476289 @default.
• W1999536411 cites W2073537077 @default.
• W1999536411 cites W2075923248 @default.
• W1999536411 cites W2078119240 @default.
• W1999536411 cites W2079618040 @default.
• W1999536411 cites W2086144601 @default.
• W1999536411 cites W2087364393 @default.
• W1999536411 cites W2088227377 @default.
• W1999536411 cites W2097057862 @default.
• W1999536411 cites W2099342322 @default.
• W1999536411 cites W2144622136 @default.
• W1999536411 cites W2170355145 @default.
• W1999536411 cites W2170715261 @default.
• W1999536411 doi "https://doi.org/10.1016/s0091-3057(97)00469-3" @default.
• W1999536411 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9610925" @default.
• W1999536411 hasPublicationYear "1998" @default.
• W1999536411 type Work @default.
• W1999536411 sameAs 1999536411 @default.
• W1999536411 citedByCount "23" @default.
• W1999536411 countsByYear W19995364112012 @default.
• W1999536411 countsByYear W19995364112013 @default.
• W1999536411 countsByYear W19995364112014 @default.
• W1999536411 countsByYear W19995364112016 @default.
• W1999536411 countsByYear W19995364112017 @default.
• W1999536411 countsByYear W19995364112019 @default.
• W1999536411 crossrefType "journal-article" @default.
• W1999536411 hasAuthorship W1999536411A5045544787 @default.
• W1999536411 hasAuthorship W1999536411A5058864296 @default.
• W1999536411 hasConcept C126322002 @default.
• W1999536411 hasConcept C134018914 @default.
• W1999536411 hasConcept C168258287 @default.
• W1999536411 hasConcept C170493617 @default.
• W1999536411 hasConcept C185592680 @default.
• W1999536411 hasConcept C2776175493 @default.
• W1999536411 hasConcept C2778173252 @default.
• W1999536411 hasConcept C2778938600 @default.
• W1999536411 hasConcept C2779547902 @default.
• W1999536411 hasConcept C2780161600 @default.
• W1999536411 hasConcept C55493867 @default.
• W1999536411 hasConcept C67018056 @default.
• W1999536411 hasConcept C71924100 @default.
• W1999536411 hasConcept C86811712 @default.
• W1999536411 hasConcept C98274493 @default.
• W1999536411 hasConceptScore W1999536411C126322002 @default.
• W1999536411 hasConceptScore W1999536411C134018914 @default.
• W1999536411 hasConceptScore W1999536411C168258287 @default.
• W1999536411 hasConceptScore W1999536411C170493617 @default.
• W1999536411 hasConceptScore W1999536411C185592680 @default.
• W1999536411 hasConceptScore W1999536411C2776175493 @default.
• W1999536411 hasConceptScore W1999536411C2778173252 @default.
• W1999536411 hasConceptScore W1999536411C2778938600 @default.
• W1999536411 hasConceptScore W1999536411C2779547902 @default.
• W1999536411 hasConceptScore W1999536411C2780161600 @default.
• W1999536411 hasConceptScore W1999536411C55493867 @default.
• W1999536411 hasConceptScore W1999536411C67018056 @default.
• W1999536411 hasConceptScore W1999536411C71924100 @default.
• W1999536411 hasConceptScore W1999536411C86811712 @default.
• W1999536411 hasConceptScore W1999536411C98274493 @default.
• W1999536411 hasIssue "1" @default.
• W1999536411 hasLocation W19995364111 @default.

• next