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- W1999553313 abstract "The effect of long-term in vivo estrogen treatment on in vitro steroidogenesis by the testes of a young man was investigated. In vitro incubation of testicular tissue of this man with 3H-pregnenolone, 3H-progesterone, 3H-androstenedione and 3H-testosterone demonstrated suppression of 17-hydroxylase activity, with little or no effect of the treatment on Δ5-3β-hydroxysteroid oxidoreductase, 5a-reductase and aromatase. Increased 20α-hydroxysteroid oxidoreductase activity was observed. Determination of intratesticular steroid concentrations led to similar conclusions." @default.
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- W1999553313 date "1977-12-01" @default.
- W1999553313 modified "2023-10-16" @default.
- W1999553313 title "In vitro steroid metabolic studies in human testes II: Metabolism of cholesterol, pregnenolone, progesterone, androstenedione and testosterone by testes of an estrogen-treated man" @default.
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- W1999553313 doi "https://doi.org/10.1016/s0039-128x(77)80019-6" @default.
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