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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1999567947> ?p ?o ?g. }

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• W1999567947 abstract "The synthesis of a novel E-ring modified keto ether analogue of camptothecin and homocamptothecin by the cascade radical annulation route is reported. The analogue, Du1441, is an isomer of homocamptothecin, but includes the α-hydroxy carbonyl functionality that camptothecin possesses and homocamptothecin lacks. Despite these similarities, the new keto ether analogue is inactive in cell assays, and implications for the structure/activity relationship are discussed." @default.
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• W1999567947 date "2002-01-01" @default.
• W1999567947 modified "2023-10-16" @default.
• W1999567947 title "Synthesis and evaluation of a novel E-ring modified α-hydroxy keto ether analogue of camptothecin" @default.
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• W1999567947 doi "https://doi.org/10.1016/s0968-0896(01)00252-8" @default.
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