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- W1999572271 endingPage "896" @default.
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- W1999572271 abstract "Microbubbles (MBs) have specific acoustic properties that make them useful as contrast agents in ultrasound imaging. The use of the MBs in clinical practice led to the development of more sensitive imaging techniques both in cardiology and radiology. Protein-MBs are typically obtained by dispersing a gas phase in the protein solution and the protein deposited/cross-linked on the gas–liquid interface stabilizes the gas core. Innovative applications of protein-MBs prompt the investigation on the properties of MBs obtained using different proteins that are able to confer them specific properties and functionality. Recently, we have synthesized stable air-filled lysozyme-MBs (LysMBs) using high-intensity ultrasound-induced emulsification of a partly reduced lysozyme in aqueous solutions. The stability of LysMBs suspension allows for post-synthetic modification of MBs surface. In the present work, the protein folded state and the biodegradability property of LysMBs were investigated by limited proteolysis. Moreover, LysMBs were coated and functionalized with a number of biomacromolecules (proteins, polysaccharides, nucleic acids). Remarkably, LysMBs show a high DNA-binding ability and protective effects of the nucleic acids from nucleases and, further, the ability to transform the bacteria cells. These results highlight on the possibility of using LysMBs for delivery of proteins and nucleic acids in prophylactic and therapeutic applications." @default.
- W1999572271 created "2016-06-24" @default.
- W1999572271 creator A5021384149 @default.
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- W1999572271 date "2011-11-18" @default.
- W1999572271 modified "2023-09-24" @default.
- W1999572271 title "Molecular properties of lysozyme-microbubbles: towards the protein and nucleic acid delivery" @default.
- W1999572271 cites W100456818 @default.
- W1999572271 cites W142282143 @default.
- W1999572271 cites W1489708565 @default.
- W1999572271 cites W1789616571 @default.
- W1999572271 cites W1963994022 @default.
- W1999572271 cites W1966289113 @default.
- W1999572271 cites W1974694293 @default.
- W1999572271 cites W1979377589 @default.
- W1999572271 cites W1989369582 @default.
- W1999572271 cites W1991295431 @default.
- W1999572271 cites W1991900060 @default.
- W1999572271 cites W1992585718 @default.
- W1999572271 cites W1993281471 @default.
- W1999572271 cites W1996545689 @default.
- W1999572271 cites W1996694523 @default.
- W1999572271 cites W1998220101 @default.
- W1999572271 cites W2009082552 @default.
- W1999572271 cites W2010655741 @default.
- W1999572271 cites W2012307975 @default.
- W1999572271 cites W2019790121 @default.
- W1999572271 cites W2022961329 @default.
- W1999572271 cites W2023962452 @default.
- W1999572271 cites W2034416132 @default.
- W1999572271 cites W2036898521 @default.
- W1999572271 cites W2040310992 @default.
- W1999572271 cites W2042036635 @default.
- W1999572271 cites W2043669567 @default.
- W1999572271 cites W2044071797 @default.
- W1999572271 cites W2044788929 @default.
- W1999572271 cites W2052199417 @default.
- W1999572271 cites W2055525983 @default.
- W1999572271 cites W2055805017 @default.
- W1999572271 cites W2056324592 @default.
- W1999572271 cites W2057466806 @default.
- W1999572271 cites W2059555046 @default.
- W1999572271 cites W2060860123 @default.
- W1999572271 cites W2070112477 @default.
- W1999572271 cites W2070683761 @default.
- W1999572271 cites W2073301363 @default.
- W1999572271 cites W2075026931 @default.
- W1999572271 cites W2077234232 @default.
- W1999572271 cites W2078267736 @default.
- W1999572271 cites W2079338670 @default.
- W1999572271 cites W2080659630 @default.
- W1999572271 cites W2081938664 @default.
- W1999572271 cites W2086495002 @default.
- W1999572271 cites W2088091588 @default.
- W1999572271 cites W2090418631 @default.
- W1999572271 cites W2092403801 @default.
- W1999572271 cites W2093988216 @default.
- W1999572271 cites W2094789831 @default.
- W1999572271 cites W2099781987 @default.
- W1999572271 cites W2100837269 @default.
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- W1999572271 cites W2117318887 @default.
- W1999572271 cites W2117959708 @default.
- W1999572271 cites W2119657344 @default.
- W1999572271 cites W2120717592 @default.
- W1999572271 cites W2123285370 @default.
- W1999572271 cites W2124763391 @default.
- W1999572271 cites W2127102027 @default.
- W1999572271 cites W2129028964 @default.
- W1999572271 cites W2135485926 @default.
- W1999572271 cites W2141806110 @default.
- W1999572271 cites W2146702187 @default.
- W1999572271 cites W2146864931 @default.
- W1999572271 cites W2154177113 @default.
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- W1999572271 cites W2163579151 @default.
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- W1999572271 doi "https://doi.org/10.1007/s00726-011-1148-z" @default.
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