FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1999583404> ?p ?o ?g. }

• W1999583404 endingPage "412" @default.
• W1999583404 startingPage "404" @default.
• W1999583404 abstract "Pyrrolidindithiocarbamate (PDTC), is a metal chelator widely used to study the activation of redox sensitive transcription factors. Recently it has been demonstrated that it manifests pro-oxidant properties. The nuclear factor-Kappa B (NF-kappaB) transcription factor can both promote cell survival and induce apoptosis depending on cell type and context in response to genotoxic stress. In our previous study we reported that in acute myelogenous leukemia CD34+ cells PDTC stimulates apoptosis, whereas in CD34+ cells of healthy volunteers PDTC was ineffective. This cytotoxicity was dependent on the generation of superoxide anion and oxidized glutathione. In this article we have shown that the pro-oxidant effect of PDTC in AML cells induces NF-kappaB activity. These findings imply a role for NF-kappaB in the survival of normal cells with respect to leukemic cells, suggesting that NF-kappaB activity and function differs according to tumor cell phenotype." @default.
• W1999583404 created "2016-06-24" @default.
• W1999583404 creator A5003798152 @default.
• W1999583404 creator A5019508579 @default.
• W1999583404 creator A5022634098 @default.
• W1999583404 creator A5033909920 @default.
• W1999583404 creator A5041497461 @default.
• W1999583404 creator A5053067949 @default.
• W1999583404 creator A5060107199 @default.
• W1999583404 date "2005-01-01" @default.
• W1999583404 modified "2023-09-27" @default.
• W1999583404 title "Pyrrolidinedithiocarbamate Induces Apoptosis in Human Acute Myelogenous Leukemic Cells Affecting NF-κB Activity" @default.
• W1999583404 cites W1497061219 @default.
• W1999583404 cites W1568529372 @default.
• W1999583404 cites W1786911182 @default.
• W1999583404 cites W1949043027 @default.
• W1999583404 cites W1965281971 @default.
• W1999583404 cites W1966653649 @default.
• W1999583404 cites W1969103034 @default.
• W1999583404 cites W1973328612 @default.
• W1999583404 cites W1980908266 @default.
• W1999583404 cites W1982062664 @default.
• W1999583404 cites W1984172682 @default.
• W1999583404 cites W1988141243 @default.
• W1999583404 cites W1993888258 @default.
• W1999583404 cites W2001946904 @default.
• W1999583404 cites W2008608024 @default.
• W1999583404 cites W2010081701 @default.
• W1999583404 cites W2027569621 @default.
• W1999583404 cites W2038377343 @default.
• W1999583404 cites W2039539436 @default.
• W1999583404 cites W2048532096 @default.
• W1999583404 cites W2057093252 @default.
• W1999583404 cites W2061557004 @default.
• W1999583404 cites W2061903251 @default.
• W1999583404 cites W2078490512 @default.
• W1999583404 cites W2081833990 @default.
• W1999583404 cites W2092105621 @default.
• W1999583404 cites W2106064881 @default.
• W1999583404 cites W2114648315 @default.
• W1999583404 cites W2118232192 @default.
• W1999583404 cites W2144377798 @default.
• W1999583404 cites W2148937254 @default.
• W1999583404 cites W2159567970 @default.
• W1999583404 cites W318722374 @default.
• W1999583404 cites W4319053763 @default.
• W1999583404 cites W51687130 @default.
• W1999583404 doi "https://doi.org/10.1081/cnv-67147" @default.
• W1999583404 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16193640" @default.
• W1999583404 hasPublicationYear "2005" @default.
• W1999583404 type Work @default.
• W1999583404 sameAs 1999583404 @default.
• W1999583404 citedByCount "9" @default.
• W1999583404 countsByYear W19995834042015 @default.
• W1999583404 countsByYear W19995834042016 @default.
• W1999583404 countsByYear W19995834042018 @default.
• W1999583404 countsByYear W19995834042021 @default.
• W1999583404 crossrefType "journal-article" @default.
• W1999583404 hasAuthorship W1999583404A5003798152 @default.
• W1999583404 hasAuthorship W1999583404A5019508579 @default.
• W1999583404 hasAuthorship W1999583404A5022634098 @default.
• W1999583404 hasAuthorship W1999583404A5033909920 @default.
• W1999583404 hasAuthorship W1999583404A5041497461 @default.
• W1999583404 hasAuthorship W1999583404A5053067949 @default.
• W1999583404 hasAuthorship W1999583404A5060107199 @default.
• W1999583404 hasConcept C10205521 @default.
• W1999583404 hasConcept C104317684 @default.
• W1999583404 hasConcept C123298856 @default.
• W1999583404 hasConcept C127716648 @default.
• W1999583404 hasConcept C151730666 @default.
• W1999583404 hasConcept C171122931 @default.
• W1999583404 hasConcept C181199279 @default.
• W1999583404 hasConcept C185592680 @default.
• W1999583404 hasConcept C190283241 @default.
• W1999583404 hasConcept C203014093 @default.
• W1999583404 hasConcept C2776151105 @default.
• W1999583404 hasConcept C2777730290 @default.
• W1999583404 hasConcept C2778461978 @default.
• W1999583404 hasConcept C2779343474 @default.
• W1999583404 hasConcept C2780795997 @default.
• W1999583404 hasConcept C28328180 @default.
• W1999583404 hasConcept C502942594 @default.
• W1999583404 hasConcept C55493867 @default.
• W1999583404 hasConcept C86339819 @default.
• W1999583404 hasConcept C86803240 @default.
• W1999583404 hasConcept C95444343 @default.
• W1999583404 hasConceptScore W1999583404C10205521 @default.
• W1999583404 hasConceptScore W1999583404C104317684 @default.
• W1999583404 hasConceptScore W1999583404C123298856 @default.
• W1999583404 hasConceptScore W1999583404C127716648 @default.
• W1999583404 hasConceptScore W1999583404C151730666 @default.
• W1999583404 hasConceptScore W1999583404C171122931 @default.
• W1999583404 hasConceptScore W1999583404C181199279 @default.
• W1999583404 hasConceptScore W1999583404C185592680 @default.
• W1999583404 hasConceptScore W1999583404C190283241 @default.
• W1999583404 hasConceptScore W1999583404C203014093 @default.
• W1999583404 hasConceptScore W1999583404C2776151105 @default.
• W1999583404 hasConceptScore W1999583404C2777730290 @default.

• next