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- W1999592945 abstract "Cyclic tetrapeptides are a class of natural products that have been shown to have broad ranging biological activities and good pharmacokinetic properties. In order to synthesise these highly strained compounds a ring contraction strategy had previously been reported. This strategy was further optimised and a suite of techniques, including the Edman degradation and mass spectrometry/mass spectrometry, were developed to enable characterisation of cyclic tetrapeptide isomers. An NMR solution structure of a cyclic tetrapeptide was also generated. To illustrate the success of this strategy a library of cyclic tetrapeptides was synthesised." @default.
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- W1999592945 date "2008-01-01" @default.
- W1999592945 modified "2023-10-16" @default.
- W1999592945 title "Cyclic tetrapeptides via the ring contraction strategy: chemical techniques useful for their identification" @default.
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- W1999592945 doi "https://doi.org/10.1039/b800464a" @default.
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