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• W1999641171 abstract "The novel natural product xyloallenoide A, isolated from the marine mangrove endophytic fungus from the South China Sea, and its diastereoisomer xyloallenoide A1, which contain N-methyl-substituted amino acids, were synthesized. The absolute configurations of the amino acid units of xyloallenoide A were finally confirmed to be L-Lys, Me-D-Val, and Me-L-Ala. This report represents a practical and attractive alternative for the synthesis of N-methyl-substituted cyclotripeptides. In the preliminary bioassay, synthetic xyloallenoide A showed marginal activities against KB (IC50=9.6 μM) and KBv200 cells (IC50=10.3 μM), and xyloallenoide A1 was inactive against KB and KBv200 cells." @default.
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• W1999641171 date "2012-06-01" @default.
• W1999641171 modified "2023-10-14" @default.
• W1999641171 title "Total Synthesis, Absolute Configuration, and Biological Activity of Xyloallenoide A" @default.
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• W1999641171 doi "https://doi.org/10.1002/hlca.201100437" @default.
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