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- W1999673587 abstract "Drug transporters mediate the uptake and elimination of drugs in various organs; therefore, having knowledge of how a transporter functions in the body would play a key role in ensuring drug efficacy in in vivo systems. In this context, we designed and synthesized [11C]dehydropravastatin, a novel PET probe that would be potentially useful for evaluation of the functions of the OATP1B1 and MRP2 transporters, based on the use of palladium(0)-mediated rapid C-[11C]methylation (viz., the rapid cross-coupling between [11C]methyl iodide and a boron intermediate)." @default.
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- W1999673587 date "2012-06-01" @default.
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- W1999673587 title "Synthesis of [11C]dehydropravastatin, a PET probe potentially useful for studying OATP1B1 and MRP2 transporters in the liver" @default.
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- W1999673587 doi "https://doi.org/10.1016/j.bmc.2012.04.051" @default.
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