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- W1999685220 abstract "Medical education is perceived as stressful. The purpose of this study was to explore the possible effect of academic examination stress on cortical long-term potentiation (LTP)-like plasticity in a group of university students. The study included nine healthy medical students (males: mean age 30.2 ± 4.3 SE) and was conducted during a major exam period (stressed) and 5 weeks later after the exams (non-stressed). Facilitatory associative plasticity was induced by paired associative stimulation (PAS) in the human motor cortex (PAS-25 protocol). In addition, students were required to fill the Perceived Stress Scale 10 (PSS) questionnaire. Sixty minutes after PAS-25 induction protocol, students showed lower amounts of potentiation during the exam period compared with after the exams ( p = 0.039). The average PSS score significantly higher during the “stressed” period ( P = 0.024). LTP-like plasticity showed an inverse correlation with the perceived stress. Academic stress appears to affect LTP-like plasticity in students. Deficit in attention and impairment of N -methyl- d -aspartate receptor-dependent neural plasticity associated with stress might underlie our findings. Larger scale studies are needed to address the interrelationship between LTP-like plasticity and academic performance." @default.
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- W1999685220 date "2013-10-01" @default.
- W1999685220 modified "2023-09-27" @default.
- W1999685220 title "P 136. The influence of academic stress on cortical plasticity" @default.
- W1999685220 doi "https://doi.org/10.1016/j.clinph.2013.04.214" @default.
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