Matches in SemOpenAlex for { <https://semopenalex.org/work/W1999688892> ?p ?o ?g. }
- W1999688892 endingPage "263" @default.
- W1999688892 startingPage "253" @default.
- W1999688892 abstract "Intracellular Ca2+ transients are evoked either by the opening of Ca2+ channels on the plasma membrane or by phospholipase C (PLC) activation resulting in IP3 production. Ca2+ wave propagation is known to occur in mechanically stimulated cells; however, it remains uncertain whether and how PLC activation is involved in intracellular Ca2+ wave propagation in mechanically stimulated cells. To answer these questions, it is indispensable to clarify the spatio-temporal relations between intracellular Ca2+ wave propagation and PLC activation. Thus, we visualized both cytosolic Ca2+ and PLC activation using a real-time dual-imaging system in individual Mardin–Darby Canine Kidney (MDCK) cells. This system allowed us to simultaneously observe intracellular Ca2+ wave propagation and PLC activation in a spatio-temporal manner in a single mechanically stimulated MDCK cell. The results showed that PLC was activated not only in the mechanically stimulated region but also in other subcellular regions in parallel with intracellular Ca2+ wave propagation. These results support a model in which PLC is involved in Ca2+ signaling amplification in mechanically stimulated cells." @default.
- W1999688892 created "2016-06-24" @default.
- W1999688892 creator A5014302800 @default.
- W1999688892 creator A5015586953 @default.
- W1999688892 creator A5030511864 @default.
- W1999688892 creator A5053672824 @default.
- W1999688892 date "2010-03-01" @default.
- W1999688892 modified "2023-10-01" @default.
- W1999688892 title "Spatio-temporal PLC activation in parallel with intracellular Ca2+ wave propagation in mechanically stimulated single MDCK cells" @default.
- W1999688892 cites W1485297825 @default.
- W1999688892 cites W1530464904 @default.
- W1999688892 cites W1599277155 @default.
- W1999688892 cites W1963560651 @default.
- W1999688892 cites W1965933207 @default.
- W1999688892 cites W1983293491 @default.
- W1999688892 cites W1983944086 @default.
- W1999688892 cites W1992555697 @default.
- W1999688892 cites W1992753280 @default.
- W1999688892 cites W2017427836 @default.
- W1999688892 cites W2018849626 @default.
- W1999688892 cites W2022783020 @default.
- W1999688892 cites W2026729475 @default.
- W1999688892 cites W2027939064 @default.
- W1999688892 cites W2028607959 @default.
- W1999688892 cites W2030891380 @default.
- W1999688892 cites W2033243150 @default.
- W1999688892 cites W2034537762 @default.
- W1999688892 cites W2034664890 @default.
- W1999688892 cites W2038407070 @default.
- W1999688892 cites W2045476408 @default.
- W1999688892 cites W2050479734 @default.
- W1999688892 cites W2051392735 @default.
- W1999688892 cites W2052517592 @default.
- W1999688892 cites W2055532277 @default.
- W1999688892 cites W2058839812 @default.
- W1999688892 cites W2064523678 @default.
- W1999688892 cites W2065520371 @default.
- W1999688892 cites W2066931615 @default.
- W1999688892 cites W2067592908 @default.
- W1999688892 cites W2070284330 @default.
- W1999688892 cites W2072459093 @default.
- W1999688892 cites W2073949037 @default.
- W1999688892 cites W2086659384 @default.
- W1999688892 cites W2088604182 @default.
- W1999688892 cites W2090429326 @default.
- W1999688892 cites W2103568761 @default.
- W1999688892 cites W2104846745 @default.
- W1999688892 cites W2135822679 @default.
- W1999688892 cites W2141518234 @default.
- W1999688892 cites W2145944113 @default.
- W1999688892 cites W2148640061 @default.
- W1999688892 cites W2154489315 @default.
- W1999688892 cites W2169731710 @default.
- W1999688892 cites W2171232910 @default.
- W1999688892 doi "https://doi.org/10.1016/j.ceca.2009.12.008" @default.
- W1999688892 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20060585" @default.
- W1999688892 hasPublicationYear "2010" @default.
- W1999688892 type Work @default.
- W1999688892 sameAs 1999688892 @default.
- W1999688892 citedByCount "11" @default.
- W1999688892 countsByYear W19996888922013 @default.
- W1999688892 countsByYear W19996888922014 @default.
- W1999688892 countsByYear W19996888922017 @default.
- W1999688892 countsByYear W19996888922018 @default.
- W1999688892 countsByYear W19996888922019 @default.
- W1999688892 countsByYear W19996888922022 @default.
- W1999688892 countsByYear W19996888922023 @default.
- W1999688892 crossrefType "journal-article" @default.
- W1999688892 hasAuthorship W1999688892A5014302800 @default.
- W1999688892 hasAuthorship W1999688892A5015586953 @default.
- W1999688892 hasAuthorship W1999688892A5030511864 @default.
- W1999688892 hasAuthorship W1999688892A5053672824 @default.
- W1999688892 hasConcept C12554922 @default.
- W1999688892 hasConcept C181199279 @default.
- W1999688892 hasConcept C185592680 @default.
- W1999688892 hasConcept C2778597717 @default.
- W1999688892 hasConcept C55493867 @default.
- W1999688892 hasConcept C62478195 @default.
- W1999688892 hasConcept C79879829 @default.
- W1999688892 hasConcept C86803240 @default.
- W1999688892 hasConcept C95444343 @default.
- W1999688892 hasConcept C98539663 @default.
- W1999688892 hasConceptScore W1999688892C12554922 @default.
- W1999688892 hasConceptScore W1999688892C181199279 @default.
- W1999688892 hasConceptScore W1999688892C185592680 @default.
- W1999688892 hasConceptScore W1999688892C2778597717 @default.
- W1999688892 hasConceptScore W1999688892C55493867 @default.
- W1999688892 hasConceptScore W1999688892C62478195 @default.
- W1999688892 hasConceptScore W1999688892C79879829 @default.
- W1999688892 hasConceptScore W1999688892C86803240 @default.
- W1999688892 hasConceptScore W1999688892C95444343 @default.
- W1999688892 hasConceptScore W1999688892C98539663 @default.
- W1999688892 hasIssue "3" @default.
- W1999688892 hasLocation W19996888921 @default.
- W1999688892 hasLocation W19996888922 @default.
- W1999688892 hasOpenAccess W1999688892 @default.
- W1999688892 hasPrimaryLocation W19996888921 @default.
- W1999688892 hasRelatedWork W1488216507 @default.