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- W1999726672 abstract "Phospholipids are not soluble in pure carbon dioxide used in supercritical flucid extraction due to their nonpolar nature. However, addition of ethanol as an entrainer makes it possible to selectively extract phoshatidylcholine (PC) from a phospholipid mixture. Phosphatidylcholine has a potential value in the pharmaceutical industry. In this study, two different models to predict the extraction behavior of phospholipids (a multicomponent system) with an entrained supercritical fluid (carbon dioxide/ethanol) were evaluated. The models developed for selective extraction of PC from a complex lecithin mixture were a mixed-flow model with an overall mass transfer coefficient as well as a shrinking-core model. Both models gave similar results in predicting the experimental data due to two main reasons: (1) shrinking-core model was developed with the perfect mixing assumption of the fluid phase, and (2) extraction of phospholipids from the lecithin mixture with SC-CO2/ethanol was a slow process." @default.
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- W1999726672 date "2003-09-01" @default.
- W1999726672 modified "2023-09-25" @default.
- W1999726672 title "MODELING OF SELECTIVE EXTRACTION OF PHOSPHATIDYLCHOLINE FROM A COMPLEX LECITHIN MIXTURE USING SUPERCRITICAL CO<sub>2</sub>/ETHANOL" @default.
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- W1999726672 doi "https://doi.org/10.1111/j.1745-4522.2003.tb00016.x" @default.
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