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- W1999739162 abstract "The clinical importance of IgG anticardiolipin antibodies was investigated in systemic lupus erythematosus (SLE). IgG anticardiolipin antibodies were found in 69 of 155 (44.5%) patients with SLE. Serial measurements of IgG anticardiolipin antibodies allowed the patients to be classified into two groups: group A, persistently positive for IgG anticardiolipin antibodies; group B, positive only in active phases. The IgG anticardiolipin antibody titre in group A was significantly higher than in group B. The incidence of thromboses, spontaneous abortions, and lupus anticoagulant in group A was significantly higher than in group B (p less than 0.05). By contrast, the incidence of renal diseases and anti-dsDNA antibodies in group B was significantly higher than in group A (p less than 0.05). This study showed that group A formed a separate subgroup of patients with SLE who had a high risk of thromboses and spontaneous abortions despite having milder disease activity." @default.
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- W1999739162 date "1990-06-01" @default.
- W1999739162 modified "2023-09-25" @default.
- W1999739162 title "Clinical importance of persistence of anticardiolipin antibodies in systemic lupus erythematosus." @default.
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- W1999739162 doi "https://doi.org/10.1136/ard.49.6.387" @default.
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