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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1999777715> ?p ?o ?g. }

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• W1999777715 abstract "The apoptotic cell death in Cal-27 cells induced by exposure to transforming growth factor-beta 1 was inhibited by the endonuclease inhibitor aurintricarboxylic acid (ATA) in a concentration-dependent fashion. In vitro studies of cytotoxicity, DNA fragmentation, and protein synthesis by Cal-27 cell lines were performed. Inhibition of cytotoxicity as well as endonucleolytic DNA cleavage was detected. ATA did not inhibit cytotoxicity either via transforming growth factor cell-surface-receptor alteration or by inhibition of macromolecular synthesis. ATA-sensitive events occurred late during treatment. These data suggest that endonucleolytic DNA cleavage is a mandatory event leading to cell death in this system." @default.
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• W1999777715 date "1996-07-01" @default.
• W1999777715 modified "2023-09-27" @default.
• W1999777715 title "Regulation of Transforming Growth Factor-β1-Mediated Apoptosis in Head and Neck Squamous Cell Carcinoma" @default.
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• W1999777715 doi "https://doi.org/10.1097/00005537-199607000-00020" @default.
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