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- W1999790662 abstract "WHEN the tissues of Craniata are treated by the technique of Takamatsu1 and of Gomorri2, alkaline phosphatase is found to be present in the cell nuclei. Willmer3 has observed that in mitosis in tissue cultures the nuclear phosphatase is concentrated on the chromosomes. One of us (J. F. D.), in collaboration with Dr. H. B. Fell, has found phosphatase on the chromosomes in tissue culture mitoses, and in the mitoses of healing wounds. That the enzyme is indeed in the cell nuclei may be shown in many ways4; for example, on heating dry rat kidney sections phosphatase not in the nuclei is destroyed more rapidly than is nuclear phosphatase, so that, by careful timing, sections may be obtained in which only the nuclei contain active phosphatase." @default.
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- W1999790662 date "1945-09-01" @default.
- W1999790662 modified "2023-09-23" @default.
- W1999790662 title "Phosphatase on Chromosomes" @default.
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- W1999790662 doi "https://doi.org/10.1038/156294a0" @default.
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