FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1999841301> ?p ?o ?g. }

• W1999841301 endingPage "2671" @default.
• W1999841301 startingPage "2658" @default.
• W1999841301 abstract "The effects of lipid chain packing and permeant size and shape on permeability across lipid bilayers have been investigated in gel and liquid crystalline dipalmitoylphosphatidylcholine (DPPC) bilayers by a combined NMR line-broadening/dynamic light scattering method using seven short-chain monocarboxylic acids (formic acid, acetic acid, propionic acid, butyric acid, valeric acid, isovaleric acid, and trimethylacetic acid) as permeants. The experimental permeability coefficients are compared with the predictions of a bulk solubility diffusion model in which the bilayer membrane is represented as a slab of bulk hexadecane. Deviations of the observed permeability coefficients (Pm) from the values predicted from solubility diffusion theory (Po) lead to the determination of a correction factor, the permeability decrement f (= Pm/Po), to account for the effects of chain ordering. The natural logarithm of f has been found to correlate linearly with the inverse of the bilayer free surface area with slopes of 25 +/- 2, 36 +/- 3, 45 +/- 8, 32 +/- 12, 33 +/- 4, 49 +/- 12, and 75 +/- 6 A2 for formic acid, acetic acid, propionic acid, butyric acid, valeric acid, isovaleric acid, and trimethylacetic acid, respectively. The slope, which measures the sensitivity of the permeability coefficient of a given permeant to bilayer chain packing, exhibits an excellent linear correlation (r = 0.94) with the minimum cross-sectional area of the permeant and a poor correlation (r = 0.59) with molecular volume, suggesting that in the bilayer interior the permeants prefer to move with their long principal axis along the bilayer normal. Based on these studies, a permeability model combining the effects of bilayer chain packing and permeant size and shape on permeability across lipid membranes is developed." @default.
• W1999841301 created "2016-06-24" @default.
• W1999841301 creator A5022255884 @default.
• W1999841301 creator A5052779766 @default.
• W1999841301 date "1998-12-01" @default.
• W1999841301 modified "2023-10-05" @default.
• W1999841301 title "Influence of Chain Ordering on the Selectivity of Dipalmitoylphosphatidylcholine Bilayer Membranes for Permeant Size and Shape" @default.
• W1999841301 cites W1968758956 @default.
• W1999841301 cites W1971064477 @default.
• W1999841301 cites W1971737783 @default.
• W1999841301 cites W1972757296 @default.
• W1999841301 cites W1976906829 @default.
• W1999841301 cites W1978525775 @default.
• W1999841301 cites W1981445035 @default.
• W1999841301 cites W1981838767 @default.
• W1999841301 cites W1987014906 @default.
• W1999841301 cites W1993327079 @default.
• W1999841301 cites W1993971811 @default.
• W1999841301 cites W1995534336 @default.
• W1999841301 cites W1996016803 @default.
• W1999841301 cites W1996794701 @default.
• W1999841301 cites W2004783238 @default.
• W1999841301 cites W2005030208 @default.
• W1999841301 cites W2019036104 @default.
• W1999841301 cites W2020747116 @default.
• W1999841301 cites W2021814718 @default.
• W1999841301 cites W2022434327 @default.
• W1999841301 cites W2023360366 @default.
• W1999841301 cites W2023621385 @default.
• W1999841301 cites W2024176837 @default.
• W1999841301 cites W2024993418 @default.
• W1999841301 cites W2025470299 @default.
• W1999841301 cites W2027150051 @default.
• W1999841301 cites W2032631686 @default.
• W1999841301 cites W2035667625 @default.
• W1999841301 cites W2036441926 @default.
• W1999841301 cites W2038225831 @default.
• W1999841301 cites W2038919684 @default.
• W1999841301 cites W2039067248 @default.
• W1999841301 cites W2044308707 @default.
• W1999841301 cites W2046602210 @default.
• W1999841301 cites W2046697069 @default.
• W1999841301 cites W2047414254 @default.
• W1999841301 cites W2051906961 @default.
• W1999841301 cites W2053575207 @default.
• W1999841301 cites W2055552159 @default.
• W1999841301 cites W2056132184 @default.
• W1999841301 cites W2058371612 @default.
• W1999841301 cites W2058783229 @default.
• W1999841301 cites W2064757248 @default.
• W1999841301 cites W2065070348 @default.
• W1999841301 cites W2066387318 @default.
• W1999841301 cites W2067236876 @default.
• W1999841301 cites W2069813518 @default.
• W1999841301 cites W2071481733 @default.
• W1999841301 cites W2071686354 @default.
• W1999841301 cites W2074342968 @default.
• W1999841301 cites W2075287982 @default.
• W1999841301 cites W2079946015 @default.
• W1999841301 cites W2085979983 @default.
• W1999841301 cites W2090651695 @default.
• W1999841301 cites W2092068407 @default.
• W1999841301 cites W2093405013 @default.
• W1999841301 cites W2093873280 @default.
• W1999841301 cites W2094875314 @default.
• W1999841301 cites W2128444449 @default.
• W1999841301 cites W2142528678 @default.
• W1999841301 cites W2144607731 @default.
• W1999841301 cites W2151155243 @default.
• W1999841301 cites W2154756937 @default.
• W1999841301 cites W2166458266 @default.
• W1999841301 cites W2169488170 @default.
• W1999841301 cites W2297576575 @default.
• W1999841301 cites W2314345990 @default.
• W1999841301 cites W2315338838 @default.
• W1999841301 cites W2317164129 @default.
• W1999841301 cites W2320222822 @default.
• W1999841301 cites W2407923760 @default.
• W1999841301 cites W2416951817 @default.
• W1999841301 doi "https://doi.org/10.1016/s0006-3495(98)77711-2" @default.
• W1999841301 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1299941" @default.
• W1999841301 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9826590" @default.
• W1999841301 hasPublicationYear "1998" @default.
• W1999841301 type Work @default.
• W1999841301 sameAs 1999841301 @default.
• W1999841301 citedByCount "139" @default.
• W1999841301 countsByYear W19998413012012 @default.
• W1999841301 countsByYear W19998413012013 @default.
• W1999841301 countsByYear W19998413012014 @default.
• W1999841301 countsByYear W19998413012015 @default.
• W1999841301 countsByYear W19998413012016 @default.
• W1999841301 countsByYear W19998413012017 @default.
• W1999841301 countsByYear W19998413012018 @default.
• W1999841301 countsByYear W19998413012019 @default.
• W1999841301 countsByYear W19998413012020 @default.
• W1999841301 countsByYear W19998413012021 @default.
• W1999841301 countsByYear W19998413012022 @default.
• W1999841301 countsByYear W19998413012023 @default.

• next