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- W1999852429 abstract "Abstract In rats up to 0.25% of an injected dose of [carboxy-14C]benzoic acid appeared in the hydrolysed urine as 2-, 3- and 4-hydroxybenzoic acids. The per cent hydroxylation depended on the initial dose and was not increased by ascorbic acid feeding. In guinea-pigs 0.038% hydroxylation occurred, only 3- and 4-hydroxybenzoic acids could be detected as metabolites and the quantities formed were the same in normal and scorbutic animals. The isomer ratio observed is not consistent with either a straightforward electrophilic or homolytic substitution and it is suggested that an electrophilic radical may be the attacking species." @default.
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- W1999852429 date "1962-05-01" @default.
- W1999852429 modified "2023-09-23" @default.
- W1999852429 title "The hydroxylation of benzoic acid by rats and guinea-pigs" @default.
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- W1999852429 doi "https://doi.org/10.1016/0006-3002(62)90180-4" @default.
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