Matches in SemOpenAlex for { <https://semopenalex.org/work/W1999890474> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W1999890474 endingPage "385" @default.
- W1999890474 startingPage "381" @default.
- W1999890474 abstract "Background: Impaired coronary artery reserve has previously been demonstrated in patients with systemic sclerosis (SSc). Both micro- and macrovascular factors are probably contributory to the underlying pathogenesis.Objectives: To examine the frequency of coronary atherosclerosis in a series of SSc patients by computed tomography coronary angiography (CTCA), a less invasive method than conventional coronary angiography, the current gold standard in the detection of coronary atherosclerosis, and to explore its clinical associations.Methods: Nineteen consecutive SSc patients [six with diffuse (dSSc) and 13 with limited disease (lSSc)] with disease duration of ≥ 3 years were recruited. Coronary calcium score and contrast angiography were examined by CT scan. Conventional cardiovascular factors and inflammatory markers were measured and correlated with CT findings.Results: The mean±SD age of these patients was 52.5±12.5 years with median disease duration of 12.5 years. Six (31.6%) patients were found to have coronary artery calcification (calcium score 13–2008). Coronary calcium was detected in one dSSc patient but contrast angiography was not performed because of interference from an in situ implantable cardiac device. Some parts of the coronary arteries were not assessable in two patients who had ectopic cardiac rhythm. Five lSSc patients had calcified plaques causing variable coronary luminal stenosis. All patients were asymptomatic. Patients with abnormal CTCA findings were more likely to be older (p < 0.001) and were less likely to have serum anti-Scl70 antibodies (p = 0.003) than those without, after Bonferroni correction.Conclusions: Coronary atherosclerosis is not uncommon in asymptomatic SSc patients. CTCA is a convenient and non-invasive method for studying coronary atherosclerosis." @default.
- W1999890474 created "2016-06-24" @default.
- W1999890474 creator A5004488408 @default.
- W1999890474 creator A5046621449 @default.
- W1999890474 creator A5065574507 @default.
- W1999890474 creator A5068252545 @default.
- W1999890474 creator A5072149062 @default.
- W1999890474 creator A5074140939 @default.
- W1999890474 creator A5078126942 @default.
- W1999890474 date "2009-01-01" @default.
- W1999890474 modified "2023-10-01" @default.
- W1999890474 title "Coronary atherosclerosis using computed tomography coronary angiography in patients with systemic sclerosis" @default.
- W1999890474 cites W1560668793 @default.
- W1999890474 cites W1986753364 @default.
- W1999890474 cites W2061512688 @default.
- W1999890474 cites W2069971192 @default.
- W1999890474 cites W2076924094 @default.
- W1999890474 cites W2092082068 @default.
- W1999890474 cites W2097409978 @default.
- W1999890474 cites W2098515297 @default.
- W1999890474 cites W2105573863 @default.
- W1999890474 cites W2109242477 @default.
- W1999890474 cites W2149024872 @default.
- W1999890474 cites W2150168622 @default.
- W1999890474 cites W2167023781 @default.
- W1999890474 doi "https://doi.org/10.1080/03009740902992979" @default.
- W1999890474 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19585378" @default.
- W1999890474 hasPublicationYear "2009" @default.
- W1999890474 type Work @default.
- W1999890474 sameAs 1999890474 @default.
- W1999890474 citedByCount "21" @default.
- W1999890474 countsByYear W19998904742012 @default.
- W1999890474 countsByYear W19998904742013 @default.
- W1999890474 countsByYear W19998904742014 @default.
- W1999890474 countsByYear W19998904742015 @default.
- W1999890474 countsByYear W19998904742016 @default.
- W1999890474 countsByYear W19998904742017 @default.
- W1999890474 countsByYear W19998904742019 @default.
- W1999890474 crossrefType "journal-article" @default.
- W1999890474 hasAuthorship W1999890474A5004488408 @default.
- W1999890474 hasAuthorship W1999890474A5046621449 @default.
- W1999890474 hasAuthorship W1999890474A5065574507 @default.
- W1999890474 hasAuthorship W1999890474A5068252545 @default.
- W1999890474 hasAuthorship W1999890474A5072149062 @default.
- W1999890474 hasAuthorship W1999890474A5074140939 @default.
- W1999890474 hasAuthorship W1999890474A5078126942 @default.
- W1999890474 hasConcept C126322002 @default.
- W1999890474 hasConcept C126838900 @default.
- W1999890474 hasConcept C164705383 @default.
- W1999890474 hasConcept C2775981168 @default.
- W1999890474 hasConcept C2776820930 @default.
- W1999890474 hasConcept C2777910003 @default.
- W1999890474 hasConcept C2778213512 @default.
- W1999890474 hasConcept C2778742706 @default.
- W1999890474 hasConcept C2780309369 @default.
- W1999890474 hasConcept C2780643987 @default.
- W1999890474 hasConcept C2909917808 @default.
- W1999890474 hasConcept C2991716557 @default.
- W1999890474 hasConcept C71924100 @default.
- W1999890474 hasConceptScore W1999890474C126322002 @default.
- W1999890474 hasConceptScore W1999890474C126838900 @default.
- W1999890474 hasConceptScore W1999890474C164705383 @default.
- W1999890474 hasConceptScore W1999890474C2775981168 @default.
- W1999890474 hasConceptScore W1999890474C2776820930 @default.
- W1999890474 hasConceptScore W1999890474C2777910003 @default.
- W1999890474 hasConceptScore W1999890474C2778213512 @default.
- W1999890474 hasConceptScore W1999890474C2778742706 @default.
- W1999890474 hasConceptScore W1999890474C2780309369 @default.
- W1999890474 hasConceptScore W1999890474C2780643987 @default.
- W1999890474 hasConceptScore W1999890474C2909917808 @default.
- W1999890474 hasConceptScore W1999890474C2991716557 @default.
- W1999890474 hasConceptScore W1999890474C71924100 @default.
- W1999890474 hasIssue "5" @default.
- W1999890474 hasLocation W19998904741 @default.
- W1999890474 hasLocation W19998904742 @default.
- W1999890474 hasOpenAccess W1999890474 @default.
- W1999890474 hasPrimaryLocation W19998904741 @default.
- W1999890474 hasRelatedWork W1989383463 @default.
- W1999890474 hasRelatedWork W2035476262 @default.
- W1999890474 hasRelatedWork W2052357082 @default.
- W1999890474 hasRelatedWork W2109132121 @default.
- W1999890474 hasRelatedWork W2117056825 @default.
- W1999890474 hasRelatedWork W2399328332 @default.
- W1999890474 hasRelatedWork W2413926756 @default.
- W1999890474 hasRelatedWork W3150523607 @default.
- W1999890474 hasRelatedWork W3201026989 @default.
- W1999890474 hasRelatedWork W4293578848 @default.
- W1999890474 hasVolume "38" @default.
- W1999890474 isParatext "false" @default.
- W1999890474 isRetracted "false" @default.
- W1999890474 magId "1999890474" @default.
- W1999890474 workType "article" @default.