Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000147201> ?p ?o ?g. }
Showing items 1 to 64 of
64
with 100 items per page.
- W2000147201 endingPage "179" @default.
- W2000147201 startingPage "174" @default.
- W2000147201 abstract "A tunable acoustic biosensor for investigating the properties of biomolecules at the solid-liquid interfaces is described. In its current, format the device can be tuned to frequencies between 6.5 MHz and 1.1 GHz in order to provide a unique detection feature: a variable evanescent wave thickness at the sensor surface. The key to its successful implementation required the careful selection of antennae designs that could induce shear acoustic waves at the solid-liquid interface. This non-contact format makes it possible to recover resonant shear acoustic waves over 100 different harmonic frequencies as a result of the electrical characteristics of the spiral coil. For testing this multifrequency sensing concept the surface of a quartz disc was exposed to solutions of immunoglobulin G (IgG) to form an adsorbed monolayer, whence protein A and IgG were added again in order to form multilayers. Spectra at frequencies between 6 and 600 MHz were generated for each successive layer and revealed two characteristic phases: an initial phase at the low megahertz frequencies consistent with the conventional Sauerbrey relation, and a possible additional phase towards the high megahertz to gigahertz frequencies, that we believe relates to the structure of the biomolecular film. This two-phase behaviour evident from differences between high and low frequencies, rather than from any distinct frequency transition, was anticipated from the reduction in evanescent wave thickness down to nanometre dimensions, and thin film resonance phenomena that are known to occur for film and fluid systems. These measurements suggested that the single element acoustic biosensor we present here may form the basis from which to generate acoustic molecular spectra, or acoustic fingerprints, in a manner akin to optical spectroscopy." @default.
- W2000147201 created "2016-06-24" @default.
- W2000147201 creator A5066362972 @default.
- W2000147201 creator A5070216575 @default.
- W2000147201 creator A5071806024 @default.
- W2000147201 creator A5073891108 @default.
- W2000147201 creator A5087351855 @default.
- W2000147201 date "2004-05-01" @default.
- W2000147201 modified "2023-09-27" @default.
- W2000147201 title "The application of the acoustic spectrophonometer to biomolecular spectrometry: a step towards acoustic‘fingerprinting’" @default.
- W2000147201 doi "https://doi.org/10.1002/jmr.666" @default.
- W2000147201 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15137026" @default.
- W2000147201 hasPublicationYear "2004" @default.
- W2000147201 type Work @default.
- W2000147201 sameAs 2000147201 @default.
- W2000147201 citedByCount "5" @default.
- W2000147201 countsByYear W20001472012014 @default.
- W2000147201 countsByYear W20001472012016 @default.
- W2000147201 crossrefType "journal-article" @default.
- W2000147201 hasAuthorship W2000147201A5066362972 @default.
- W2000147201 hasAuthorship W2000147201A5070216575 @default.
- W2000147201 hasAuthorship W2000147201A5071806024 @default.
- W2000147201 hasAuthorship W2000147201A5073891108 @default.
- W2000147201 hasAuthorship W2000147201A5087351855 @default.
- W2000147201 hasConcept C121332964 @default.
- W2000147201 hasConcept C160756335 @default.
- W2000147201 hasConcept C162954803 @default.
- W2000147201 hasConcept C171250308 @default.
- W2000147201 hasConcept C192562407 @default.
- W2000147201 hasConcept C204723758 @default.
- W2000147201 hasConcept C24890656 @default.
- W2000147201 hasConcept C49040817 @default.
- W2000147201 hasConcept C7070889 @default.
- W2000147201 hasConceptScore W2000147201C121332964 @default.
- W2000147201 hasConceptScore W2000147201C160756335 @default.
- W2000147201 hasConceptScore W2000147201C162954803 @default.
- W2000147201 hasConceptScore W2000147201C171250308 @default.
- W2000147201 hasConceptScore W2000147201C192562407 @default.
- W2000147201 hasConceptScore W2000147201C204723758 @default.
- W2000147201 hasConceptScore W2000147201C24890656 @default.
- W2000147201 hasConceptScore W2000147201C49040817 @default.
- W2000147201 hasConceptScore W2000147201C7070889 @default.
- W2000147201 hasIssue "3" @default.
- W2000147201 hasLocation W20001472011 @default.
- W2000147201 hasLocation W20001472012 @default.
- W2000147201 hasOpenAccess W2000147201 @default.
- W2000147201 hasPrimaryLocation W20001472011 @default.
- W2000147201 hasRelatedWork W2101753782 @default.
- W2000147201 hasRelatedWork W2108465531 @default.
- W2000147201 hasRelatedWork W2122543713 @default.
- W2000147201 hasRelatedWork W2147004894 @default.
- W2000147201 hasRelatedWork W2972790680 @default.
- W2000147201 hasRelatedWork W4205544315 @default.
- W2000147201 hasRelatedWork W4234572662 @default.
- W2000147201 hasRelatedWork W4246364066 @default.
- W2000147201 hasRelatedWork W4248716364 @default.
- W2000147201 hasRelatedWork W4299808493 @default.
- W2000147201 hasVolume "17" @default.
- W2000147201 isParatext "false" @default.
- W2000147201 isRetracted "false" @default.
- W2000147201 magId "2000147201" @default.
- W2000147201 workType "article" @default.