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- W2000155751 abstract "Disseminated intravascular coagulation (DIC) is a syndrome characterized by a systemic activation of coagulation leading to the intravascular deposition of fibrin in the (micro) vasculature and the simultaneous consumption of coagulation factors and platelets. The occurrence of microvascular thrombosis as a consequence of DIC is underscored by pathological, experimental and clinical findings, demonstrating a link between DIC and organ dysfunction. Pathogenetic pathways that play a role in the development of DIC include tissue factor-dependent activation of coagulation, defective physiological anticoagulant pathways (such as the antithrombin system and the protein C system), and impaired fibrinolysis, caused by elevated levels of plasminogen activator inhibitor type 1. Novel therapeutic strategies are based on current insights into the pathogenesis of DIC, and include anticoagulant strategies (eg, directed at tissue factor) and strategies to restore physiological anticoagulant pathways (such as activated protein C concentrate)." @default.
- W2000155751 created "2016-06-24" @default.
- W2000155751 creator A5038678186 @default.
- W2000155751 date "2005-07-01" @default.
- W2000155751 modified "2023-10-01" @default.
- W2000155751 title "Disseminated Intravascular Coagulation: What's New?" @default.
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- W2000155751 cites W1544112473 @default.
- W2000155751 cites W1554085014 @default.
- W2000155751 cites W1735086107 @default.
- W2000155751 cites W1905363000 @default.
- W2000155751 cites W1932895848 @default.
- W2000155751 cites W1971938388 @default.
- W2000155751 cites W1974031812 @default.
- W2000155751 cites W1980119671 @default.
- W2000155751 cites W1980233581 @default.
- W2000155751 cites W1982149026 @default.
- W2000155751 cites W1985933648 @default.
- W2000155751 cites W1987775704 @default.
- W2000155751 cites W1994318568 @default.
- W2000155751 cites W1997309182 @default.
- W2000155751 cites W1998007948 @default.
- W2000155751 cites W2007591854 @default.
- W2000155751 cites W2011356881 @default.
- W2000155751 cites W2017700181 @default.
- W2000155751 cites W2018745526 @default.
- W2000155751 cites W2020230931 @default.
- W2000155751 cites W2020513354 @default.
- W2000155751 cites W2021978469 @default.
- W2000155751 cites W2031395992 @default.
- W2000155751 cites W2038546354 @default.
- W2000155751 cites W2043788794 @default.
- W2000155751 cites W2046009388 @default.
- W2000155751 cites W2046650653 @default.
- W2000155751 cites W2049209098 @default.
- W2000155751 cites W2053367545 @default.
- W2000155751 cites W2057808949 @default.
- W2000155751 cites W2064827862 @default.
- W2000155751 cites W2065699955 @default.
- W2000155751 cites W2074188685 @default.
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- W2000155751 cites W233151749 @default.
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- W2000155751 cites W289492899 @default.
- W2000155751 cites W335124151 @default.
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- W2000155751 doi "https://doi.org/10.1016/j.ccc.2005.02.001" @default.
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