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• W2000170148 abstract "Stimulation of central angiotensin receptors promotes, among others, drinking behaviour, stimulation of natriuresis and increased release of vasopressin. Angiotensin (ANG II)-containing pathways in the lamina terminalis and the hypothalamic paraventricular (PVN) and supraoptic (SON) nuclei, brain areas involved in the regulation of body fluid homeostasis, have been described. All these areas express predominantly AT1 receptors. The drinking response and the vasopressin release to centrally administered ANG II are mediated by AT1 receptors, while AT2 receptors exert inhibitory effects. Evidence for the involvement of the catecholaminergic and angiotensinergic pathways in the PVN and SON in mediating the ANG 11-induced release of vasopressin is presented. ANG I1 is released in the PVN upon local osmotic stimulation and water deprivation. Finally, we present evidence that activation of central angiotensinergic receptors, water deprivation, or hypertonicity induce transcription of immediate-early genes and expression of the respective proteins in the lamina terminalis and in the PVN and SON. The summarized data implicate ANG I1 as a neuromodulator/neurotransmitter in central control of body fluid and electrolyte homeostasis." @default.
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• W2000170148 date "1995-01-01" @default.
• W2000170148 modified "2023-09-26" @default.
• W2000170148 title "Angiotensin as Neuromodulator/Neurotransmitter in Central Control of Body Fluid and Electrolyte Homeostasis" @default.
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• W2000170148 doi "https://doi.org/10.3109/10641969509087071" @default.
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