FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000180786> ?p ?o ?g. }

• W2000180786 endingPage "191" @default.
• W2000180786 startingPage "186" @default.
• W2000180786 abstract "Diet supplementation and/or modulation is an important strategy to significantly improve human health. The search of plants as additional sources of bioactive phenolic compounds is relevant in this context. The aqueous extract of Hibiscus sabdariffa is rich in anthocyanins and other phenolic compounds including hydroxycitric and chlorogenic acids. Using this extract we have shown an effective protection of cultured peripheral blood mononuclear cells from the cellular death induced by H(2)O(2) and a significant role in the production of inflammatory cytokines. In vitro, the extract promotes the production of IL-6 and IL-8 and decreases the concentration of MCP-1 in supernatants in a dose-dependent manner. In humans, the ingestion of an acute dose of the extract (10g) was well tolerated and decreased plasma MCP-1 concentrations significantly without further effects on other cytokines. This effect was not due to a concomitant increase in the antioxidant capacity of plasma. Instead, its mechanisms probably involve a direct inhibition of inflammatory and/or metabolic pathways responsible for MCP-1 production, and may be relevant in inflammatory and chronic conditions in which the role of MCP-1 is well established. If beneficial effects are confirmed in patients, Hibiscus sabdariffa could be considered a valuable traditional herbal medicine for the treatment of chronic inflammatory diseases with the advantage of being devoid of caloric value or potential alcohol toxicity." @default.
• W2000180786 created "2016-06-24" @default.
• W2000180786 creator A5001747071 @default.
• W2000180786 creator A5005699800 @default.
• W2000180786 creator A5007710630 @default.
• W2000180786 creator A5029784262 @default.
• W2000180786 creator A5037174678 @default.
• W2000180786 creator A5049137412 @default.
• W2000180786 creator A5053780005 @default.
• W2000180786 creator A5063130568 @default.
• W2000180786 creator A5081661175 @default.
• W2000180786 creator A5088797858 @default.
• W2000180786 date "2010-03-01" @default.
• W2000180786 modified "2023-10-18" @default.
• W2000180786 title "The aqueous extract of Hibiscus sabdariffa calices modulates the production of monocyte chemoattractant protein-1 in humans" @default.
• W2000180786 cites W1964790590 @default.
• W2000180786 cites W1966133808 @default.
• W2000180786 cites W1966428624 @default.
• W2000180786 cites W1970632381 @default.
• W2000180786 cites W1973170823 @default.
• W2000180786 cites W1975375148 @default.
• W2000180786 cites W1992915466 @default.
• W2000180786 cites W1999276977 @default.
• W2000180786 cites W2001013977 @default.
• W2000180786 cites W2013351155 @default.
• W2000180786 cites W2019580308 @default.
• W2000180786 cites W2026529975 @default.
• W2000180786 cites W2032695537 @default.
• W2000180786 cites W2034618818 @default.
• W2000180786 cites W2067938765 @default.
• W2000180786 cites W2073805013 @default.
• W2000180786 cites W2079950713 @default.
• W2000180786 cites W2080452926 @default.
• W2000180786 cites W2084484561 @default.
• W2000180786 cites W2093979148 @default.
• W2000180786 cites W2094302532 @default.
• W2000180786 cites W2100993551 @default.
• W2000180786 cites W2109914073 @default.
• W2000180786 cites W2114315567 @default.
• W2000180786 cites W2116294643 @default.
• W2000180786 cites W2124385784 @default.
• W2000180786 cites W2141832633 @default.
• W2000180786 cites W2162400053 @default.
• W2000180786 cites W2163573194 @default.
• W2000180786 cites W4322388490 @default.
• W2000180786 cites W71511797 @default.
• W2000180786 doi "https://doi.org/10.1016/j.phymed.2009.08.006" @default.
• W2000180786 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19765963" @default.
• W2000180786 hasPublicationYear "2010" @default.
• W2000180786 type Work @default.
• W2000180786 sameAs 2000180786 @default.
• W2000180786 citedByCount "83" @default.
• W2000180786 countsByYear W20001807862012 @default.
• W2000180786 countsByYear W20001807862013 @default.
• W2000180786 countsByYear W20001807862014 @default.
• W2000180786 countsByYear W20001807862015 @default.
• W2000180786 countsByYear W20001807862016 @default.
• W2000180786 countsByYear W20001807862017 @default.
• W2000180786 countsByYear W20001807862018 @default.
• W2000180786 countsByYear W20001807862019 @default.
• W2000180786 countsByYear W20001807862020 @default.
• W2000180786 countsByYear W20001807862021 @default.
• W2000180786 countsByYear W20001807862022 @default.
• W2000180786 countsByYear W20001807862023 @default.
• W2000180786 crossrefType "journal-article" @default.
• W2000180786 hasAuthorship W2000180786A5001747071 @default.
• W2000180786 hasAuthorship W2000180786A5005699800 @default.
• W2000180786 hasAuthorship W2000180786A5007710630 @default.
• W2000180786 hasAuthorship W2000180786A5029784262 @default.
• W2000180786 hasAuthorship W2000180786A5037174678 @default.
• W2000180786 hasAuthorship W2000180786A5049137412 @default.
• W2000180786 hasAuthorship W2000180786A5053780005 @default.
• W2000180786 hasAuthorship W2000180786A5063130568 @default.
• W2000180786 hasAuthorship W2000180786A5081661175 @default.
• W2000180786 hasAuthorship W2000180786A5088797858 @default.
• W2000180786 hasConcept C116263406 @default.
• W2000180786 hasConcept C137061746 @default.
• W2000180786 hasConcept C151730666 @default.
• W2000180786 hasConcept C164027704 @default.
• W2000180786 hasConcept C178790620 @default.
• W2000180786 hasConcept C185592680 @default.
• W2000180786 hasConcept C202751555 @default.
• W2000180786 hasConcept C203014093 @default.
• W2000180786 hasConcept C2776914184 @default.
• W2000180786 hasConcept C2778004101 @default.
• W2000180786 hasConcept C2779343474 @default.
• W2000180786 hasConcept C2780117898 @default.
• W2000180786 hasConcept C2781184567 @default.
• W2000180786 hasConcept C29730261 @default.
• W2000180786 hasConcept C2992330530 @default.
• W2000180786 hasConcept C31903555 @default.
• W2000180786 hasConcept C55493867 @default.
• W2000180786 hasConcept C71924100 @default.
• W2000180786 hasConcept C86803240 @default.
• W2000180786 hasConcept C98274493 @default.
• W2000180786 hasConceptScore W2000180786C116263406 @default.
• W2000180786 hasConceptScore W2000180786C137061746 @default.
• W2000180786 hasConceptScore W2000180786C151730666 @default.

• next