FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000204810> ?p ?o ?g. }

• W2000204810 endingPage "728" @default.
• W2000204810 startingPage "723" @default.
• W2000204810 abstract "Genetic variation in the perilipin (PLIN) gene may play a role in the etiology and treatment of obesity.To examine different polymorphisms in the PLIN gene in relation to body-weight regulation.118 subjects followed a 6 wk VLCD, followed by 1 year weight maintenance. Body-weight (BW), body composition, leptin concentration, and polymorphisms of the PLIN gene: PLIN1:rs2289487, PLIN4:rs894160, PLIN6:rs1052700, PLIN5:rs2304795 and PLIN7:rs 2304796 were determined.BW loss during VLCD was 7.0+/-3.1 kg (p<0.05), and BW regain was 3.7+/-1.4 kg (p<0.05), including changes in body mass index (BMI), waist-circumference, body-composition and leptin concentrations (p<0.05). Linkage disequilibria were observed between PLIN1 and PLIN4: D' >0.9, r2=0.72; PLIN5 and PLIN7: D' >0.9, r2=0.85. In men, body weight, BMI, waist circumference, body fat, leptin concentrations were significantly lower for the haplotype of PLIN1 (C-alleles) and PLIN4 (A-alleles). In women weight loss and loss of fat mass were larger for the haplotype of PLIN1 (C-alleles) and PLIN4 (A-alleles). For PLIN6 genotypes body weight and body fat were lower for homozygotes of the minor allele (T/T) in the men; in the women leptin concentrations were lower. The haplotype of PLIN5 and PLIN7 consisting of A/G and G/G of PLIN5 and A/A of PLIN7 showed a reduction in FM: 5.9+/-0.6 kg vs 3.1+/-0.4 kg, % body fat: 5.5+/-0.6% vs 2.2+/-0.2%, and leptin: 20.5+/-10.8 ng/ml vs 12.9+/-6.7 ng/ml over time in the women (p<0.05).Since the haplotype of the minor alleles PLIN1-4, PLIN5-7 and PLIN6, was related to body-weight regulation at a lower level of body-weight in the men as well in the women we conclude that the PLIN1-4, 6, and 5-7 locus appears as a genetic influencer of obesity risk in humans." @default.
• W2000204810 created "2016-06-24" @default.
• W2000204810 creator A5001663884 @default.
• W2000204810 creator A5017516588 @default.
• W2000204810 creator A5019652192 @default.
• W2000204810 creator A5061625650 @default.
• W2000204810 creator A5077982658 @default.
• W2000204810 creator A5078110189 @default.
• W2000204810 creator A5081027517 @default.
• W2000204810 date "2009-03-01" @default.
• W2000204810 modified "2023-09-23" @default.
• W2000204810 title "Relationship between perilipin gene polymorphisms and body weight and body composition during weight loss and weight maintenance" @default.
• W2000204810 cites W1504753880 @default.
• W2000204810 cites W1509818253 @default.
• W2000204810 cites W1540864797 @default.
• W2000204810 cites W1808407909 @default.
• W2000204810 cites W1976879072 @default.
• W2000204810 cites W1986914839 @default.
• W2000204810 cites W2022071831 @default.
• W2000204810 cites W2026990037 @default.
• W2000204810 cites W2046965641 @default.
• W2000204810 cites W2054397642 @default.
• W2000204810 cites W2055443182 @default.
• W2000204810 cites W2066608222 @default.
• W2000204810 cites W2077917083 @default.
• W2000204810 cites W2085617663 @default.
• W2000204810 cites W2096519088 @default.
• W2000204810 cites W2096786656 @default.
• W2000204810 cites W2107987986 @default.
• W2000204810 cites W2121202701 @default.
• W2000204810 cites W2127376370 @default.
• W2000204810 cites W2134860420 @default.
• W2000204810 cites W2138153633 @default.
• W2000204810 cites W2146776863 @default.
• W2000204810 cites W2170063942 @default.
• W2000204810 cites W4229881459 @default.
• W2000204810 cites W4362222419 @default.
• W2000204810 doi "https://doi.org/10.1016/j.physbeh.2009.01.011" @default.
• W2000204810 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19385027" @default.
• W2000204810 hasPublicationYear "2009" @default.
• W2000204810 type Work @default.
• W2000204810 sameAs 2000204810 @default.
• W2000204810 citedByCount "37" @default.
• W2000204810 countsByYear W20002048102012 @default.
• W2000204810 countsByYear W20002048102013 @default.
• W2000204810 countsByYear W20002048102014 @default.
• W2000204810 countsByYear W20002048102015 @default.
• W2000204810 countsByYear W20002048102016 @default.
• W2000204810 countsByYear W20002048102017 @default.
• W2000204810 countsByYear W20002048102018 @default.
• W2000204810 countsByYear W20002048102019 @default.
• W2000204810 countsByYear W20002048102020 @default.
• W2000204810 countsByYear W20002048102021 @default.
• W2000204810 countsByYear W20002048102022 @default.
• W2000204810 countsByYear W20002048102023 @default.
• W2000204810 crossrefType "journal-article" @default.
• W2000204810 hasAuthorship W2000204810A5001663884 @default.
• W2000204810 hasAuthorship W2000204810A5017516588 @default.
• W2000204810 hasAuthorship W2000204810A5019652192 @default.
• W2000204810 hasAuthorship W2000204810A5061625650 @default.
• W2000204810 hasAuthorship W2000204810A5077982658 @default.
• W2000204810 hasAuthorship W2000204810A5078110189 @default.
• W2000204810 hasAuthorship W2000204810A5081027517 @default.
• W2000204810 hasConcept C104317684 @default.
• W2000204810 hasConcept C126322002 @default.
• W2000204810 hasConcept C134018914 @default.
• W2000204810 hasConcept C140985366 @default.
• W2000204810 hasConcept C171089720 @default.
• W2000204810 hasConcept C180754005 @default.
• W2000204810 hasConcept C197754878 @default.
• W2000204810 hasConcept C2776193436 @default.
• W2000204810 hasConcept C2780221984 @default.
• W2000204810 hasConcept C2780613262 @default.
• W2000204810 hasConcept C39567582 @default.
• W2000204810 hasConcept C511355011 @default.
• W2000204810 hasConcept C54355233 @default.
• W2000204810 hasConcept C544821477 @default.
• W2000204810 hasConcept C71924100 @default.
• W2000204810 hasConcept C86803240 @default.
• W2000204810 hasConceptScore W2000204810C104317684 @default.
• W2000204810 hasConceptScore W2000204810C126322002 @default.
• W2000204810 hasConceptScore W2000204810C134018914 @default.
• W2000204810 hasConceptScore W2000204810C140985366 @default.
• W2000204810 hasConceptScore W2000204810C171089720 @default.
• W2000204810 hasConceptScore W2000204810C180754005 @default.
• W2000204810 hasConceptScore W2000204810C197754878 @default.
• W2000204810 hasConceptScore W2000204810C2776193436 @default.
• W2000204810 hasConceptScore W2000204810C2780221984 @default.
• W2000204810 hasConceptScore W2000204810C2780613262 @default.
• W2000204810 hasConceptScore W2000204810C39567582 @default.
• W2000204810 hasConceptScore W2000204810C511355011 @default.
• W2000204810 hasConceptScore W2000204810C54355233 @default.
• W2000204810 hasConceptScore W2000204810C544821477 @default.
• W2000204810 hasConceptScore W2000204810C71924100 @default.
• W2000204810 hasConceptScore W2000204810C86803240 @default.
• W2000204810 hasIssue "4-5" @default.
• W2000204810 hasLocation W20002048101 @default.
• W2000204810 hasLocation W20002048102 @default.

• next