FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000205893> ?p ?o ?g. }

• W2000205893 endingPage "308" @default.
• W2000205893 startingPage "302" @default.
• W2000205893 abstract "To assess the efficacy of glutamine (Gln) dipeptide-enriched total parenteral nutrition (TPN) on selected metabolic, immunologic, and clinical variables in surgical patients.Depletion of Gln stores might lead to severe clinical complications. Recent studies indicate that the parenteral provision of Gln or Gln-containing dipeptides improves nitrogen balance, maintains the intracellular Gln pool, preserves intestinal permeability and absorption, and shortens hospital stay.Twenty-eight patients (age range, 42-86 years, mean 68 years) undergoing elective abdominal surgery were allocated, after randomization, to two groups to receive isonitrogenous (0.24 g nitrogen kg(-1) day(-1)) and isoenergetic (29 kcal/122 kJ kg(-1) day(-1)) TPN over 5 days. Controls received 1.5 g of amino acids kg(-1) day(-1), and the test group received 1.2 g of amino acids and 0.3 g of L-alanyl-L-glutamine (Ala-Gln) kg(-1) day(-1). Venous heparinized blood samples were obtained before surgery and on days 1, 3, and 6 after surgery for routine clinical chemistry and for the measurement of plasma free amino acids. Lymphocytes were counted and the generation of cysteinyl-leukotrienes from polymorphonuclear neutrophil granulocytes was analyzed before surgery and on days 1 and 6 after surgery. Nitrogen balances were calculated postoperatively on days 2, 3, 4, and 5.No side effects or complaints were noted. Patients receiving Gln dipeptide revealed improved nitrogen balances (cumulative balance over 5 days: -7.9 +/- 3.6 vs. -23.0 +/- 2.6 g nitrogen), improved lymphocyte recovery on day 6 (2.41 +/- 0.27 vs. 1.52 +/- 0.17 lymphocytes/nL) and improved generation of cysteinyl-leukotrienes from polymorphonuclear neutrophil granulocytes (25.7 +/- 4.89 vs. 5.03 +/- 3.11 ng/mL). Postoperative hospital stay was 6.2 days shorter in the dipeptide-supplemented group.We confirm the beneficial effects of Gln dipeptide-supplemented TPN on nitrogen economy, maintenance of plasma Gln concentration, lymphocyte recovery, cysteinyl-leukotriene generation, and shortened hospital stay in surgical patients." @default.
• W2000205893 created "2016-06-24" @default.
• W2000205893 creator A5002497288 @default.
• W2000205893 creator A5007265205 @default.
• W2000205893 creator A5007430475 @default.
• W2000205893 creator A5039986893 @default.
• W2000205893 creator A5041657331 @default.
• W2000205893 creator A5045468681 @default.
• W2000205893 creator A5072989515 @default.
• W2000205893 creator A5083730981 @default.
• W2000205893 date "1998-02-01" @default.
• W2000205893 modified "2023-10-17" @default.
• W2000205893 title "Total Parenteral Nutrition With Glutamine Dipeptide After Major Abdominal Surgery" @default.
• W2000205893 cites W1812467831 @default.
• W2000205893 cites W1935064934 @default.
• W2000205893 cites W1964699291 @default.
• W2000205893 cites W1965333491 @default.
• W2000205893 cites W1966278199 @default.
• W2000205893 cites W1966608688 @default.
• W2000205893 cites W1976935047 @default.
• W2000205893 cites W1984020678 @default.
• W2000205893 cites W1985685526 @default.
• W2000205893 cites W1990994515 @default.
• W2000205893 cites W2026056838 @default.
• W2000205893 cites W2027217596 @default.
• W2000205893 cites W2029559453 @default.
• W2000205893 cites W2038833653 @default.
• W2000205893 cites W2045603080 @default.
• W2000205893 cites W2048438620 @default.
• W2000205893 cites W2061998755 @default.
• W2000205893 cites W2065798491 @default.
• W2000205893 cites W2072258272 @default.
• W2000205893 cites W2081117020 @default.
• W2000205893 cites W2085752184 @default.
• W2000205893 cites W2085918483 @default.
• W2000205893 cites W2086516047 @default.
• W2000205893 cites W2091454906 @default.
• W2000205893 cites W2096728158 @default.
• W2000205893 cites W2139949523 @default.
• W2000205893 cites W2159138337 @default.
• W2000205893 cites W2166569420 @default.
• W2000205893 cites W2169002591 @default.
• W2000205893 cites W2174704610 @default.
• W2000205893 cites W2178457981 @default.
• W2000205893 cites W2384408522 @default.
• W2000205893 cites W2397829668 @default.
• W2000205893 cites W2400782206 @default.
• W2000205893 cites W2401323754 @default.
• W2000205893 cites W2418262331 @default.
• W2000205893 cites W2424956979 @default.
• W2000205893 cites W2997471696 @default.
• W2000205893 cites W2417132556 @default.
• W2000205893 doi "https://doi.org/10.1097/00000658-199802000-00022" @default.
• W2000205893 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1191250" @default.
• W2000205893 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9488531" @default.
• W2000205893 hasPublicationYear "1998" @default.
• W2000205893 type Work @default.
• W2000205893 sameAs 2000205893 @default.
• W2000205893 citedByCount "224" @default.
• W2000205893 countsByYear W20002058932012 @default.
• W2000205893 countsByYear W20002058932013 @default.
• W2000205893 countsByYear W20002058932014 @default.
• W2000205893 countsByYear W20002058932015 @default.
• W2000205893 countsByYear W20002058932016 @default.
• W2000205893 countsByYear W20002058932017 @default.
• W2000205893 countsByYear W20002058932018 @default.
• W2000205893 countsByYear W20002058932019 @default.
• W2000205893 countsByYear W20002058932020 @default.
• W2000205893 countsByYear W20002058932021 @default.
• W2000205893 countsByYear W20002058932022 @default.
• W2000205893 countsByYear W20002058932023 @default.
• W2000205893 crossrefType "journal-article" @default.
• W2000205893 hasAuthorship W2000205893A5002497288 @default.
• W2000205893 hasAuthorship W2000205893A5007265205 @default.
• W2000205893 hasAuthorship W2000205893A5007430475 @default.
• W2000205893 hasAuthorship W2000205893A5039986893 @default.
• W2000205893 hasAuthorship W2000205893A5041657331 @default.
• W2000205893 hasAuthorship W2000205893A5045468681 @default.
• W2000205893 hasAuthorship W2000205893A5072989515 @default.
• W2000205893 hasAuthorship W2000205893A5083730981 @default.
• W2000205893 hasBestOaLocation W20002058932 @default.
• W2000205893 hasConcept C121332964 @default.
• W2000205893 hasConcept C126322002 @default.
• W2000205893 hasConcept C141071460 @default.
• W2000205893 hasConcept C185592680 @default.
• W2000205893 hasConcept C2779138802 @default.
• W2000205893 hasConcept C2779349466 @default.
• W2000205893 hasConcept C2780120127 @default.
• W2000205893 hasConcept C42219234 @default.
• W2000205893 hasConcept C515207424 @default.
• W2000205893 hasConcept C537208039 @default.
• W2000205893 hasConcept C55493867 @default.
• W2000205893 hasConcept C62520636 @default.
• W2000205893 hasConcept C71924100 @default.
• W2000205893 hasConcept C78722104 @default.
• W2000205893 hasConcept C8101879 @default.
• W2000205893 hasConcept C90924648 @default.
• W2000205893 hasConceptScore W2000205893C121332964 @default.

• next