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- W2000206182 abstract "Examination was made for influence of sympathetic innervation on the discharge of receptors of otherwise de-efferented muscle. Firing of units in the cat's gastrocnemius was monitored in filaments of dorsal roots while repetitive electrical stimuli were given to the distal stump of one lumbar sympathetic trunk. A characteristic response, consisting of a delayed and gradual acceleration followed by more or less abrupt cessation of firing, was found from both spindle and tendon organ afferents. Blood flow through the leg was markedly reduced during stimulation. This observation and the failure of the full effect to appear when vasoconstriction was blocked, as well as the similarity of the effect to that obtained on the same afferent during compression of the arterial supply, suggest that the response arose mainly as the indirect result of vasoconstriction. Masked by the full response, there may also be a lesser acceleratory effect which was revealed by sympathetic stimulation in the cat under the influence of the adrenergic blocking agent phenoxybenzamine and which was reproduced in some animals by small intra-arterial injections of epinephrine. Slowness in onset of this acceleration following sympathetic stimulation suggests that humoral sensitization of the peripheral endings was the cause, rather than direct motor innervation of intrafusal fibers." @default.
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- W2000206182 date "1960-02-01" @default.
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- W2000206182 title "Response of muscle spindles to stimulation of the sympathetic trunk" @default.
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- W2000206182 doi "https://doi.org/10.1016/0014-4886(60)90044-3" @default.
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