Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000206525> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2000206525 abstract "Preterm labor is associated with the release of various cytokines that play an important role in its pathophysiology. In preterm labor, tocolytics are used to inhibit uterine contractions and prolong gestation. We tested the hypothesis that tocolytics alter endotoxin-induced interleukin (IL-8) production from amniotic and decidual cells in vitro. Amniotic and decidual cells were isolated from patients undergoing elective repeat cesarean section at term. Cells were grown in tissue culture flasks. Cells were subsequently incubated with 100 ng/ml of endotoxin in 24 well plates in the presence of increasing concentrations of magnesium sulfate, nifedipine and terbutaline. After 24 h, IL-8 levels in each well were measured by ELISA. Endotoxin caused a significant elevation in IL-8 production in both amniotic and decidual cells. Magnesium sulfate dose dependently inhibited the endotoxin-stimulated IL-8 production in both decidual and amniotic cells. However, nifedipine and terbutaline did not significantly affect IL-8 production in either cell type. In conclusion, magnesium sulfate differentially suppresses endotoxin-stimulated IL-8 production in amniotic and decidual cells in vitro. The cellular mechanisms of this suppression and its clinical relevance in the setting of preterm labor merit further investigation." @default.
- W2000206525 created "2016-06-24" @default.
- W2000206525 creator A5055302960 @default.
- W2000206525 creator A5078489891 @default.
- W2000206525 date "2003-12-01" @default.
- W2000206525 modified "2023-09-23" @default.
- W2000206525 title "Effect of tocolytics on interleukin-8 production by human amniotic and decidual cells" @default.
- W2000206525 doi "https://doi.org/10.1016/j.ajog.2003.10.395" @default.
- W2000206525 hasPublicationYear "2003" @default.
- W2000206525 type Work @default.
- W2000206525 sameAs 2000206525 @default.
- W2000206525 citedByCount "0" @default.
- W2000206525 crossrefType "journal-article" @default.
- W2000206525 hasAuthorship W2000206525A5055302960 @default.
- W2000206525 hasAuthorship W2000206525A5078489891 @default.
- W2000206525 hasConcept C126322002 @default.
- W2000206525 hasConcept C134018914 @default.
- W2000206525 hasConcept C16685009 @default.
- W2000206525 hasConcept C172680121 @default.
- W2000206525 hasConcept C203014093 @default.
- W2000206525 hasConcept C2776042228 @default.
- W2000206525 hasConcept C2776953305 @default.
- W2000206525 hasConcept C2778194526 @default.
- W2000206525 hasConcept C2778690821 @default.
- W2000206525 hasConcept C2779234561 @default.
- W2000206525 hasConcept C2780197806 @default.
- W2000206525 hasConcept C2780252434 @default.
- W2000206525 hasConcept C2780931799 @default.
- W2000206525 hasConcept C2781107390 @default.
- W2000206525 hasConcept C3019152611 @default.
- W2000206525 hasConcept C46973012 @default.
- W2000206525 hasConcept C54355233 @default.
- W2000206525 hasConcept C71924100 @default.
- W2000206525 hasConcept C74172505 @default.
- W2000206525 hasConcept C86803240 @default.
- W2000206525 hasConceptScore W2000206525C126322002 @default.
- W2000206525 hasConceptScore W2000206525C134018914 @default.
- W2000206525 hasConceptScore W2000206525C16685009 @default.
- W2000206525 hasConceptScore W2000206525C172680121 @default.
- W2000206525 hasConceptScore W2000206525C203014093 @default.
- W2000206525 hasConceptScore W2000206525C2776042228 @default.
- W2000206525 hasConceptScore W2000206525C2776953305 @default.
- W2000206525 hasConceptScore W2000206525C2778194526 @default.
- W2000206525 hasConceptScore W2000206525C2778690821 @default.
- W2000206525 hasConceptScore W2000206525C2779234561 @default.
- W2000206525 hasConceptScore W2000206525C2780197806 @default.
- W2000206525 hasConceptScore W2000206525C2780252434 @default.
- W2000206525 hasConceptScore W2000206525C2780931799 @default.
- W2000206525 hasConceptScore W2000206525C2781107390 @default.
- W2000206525 hasConceptScore W2000206525C3019152611 @default.
- W2000206525 hasConceptScore W2000206525C46973012 @default.
- W2000206525 hasConceptScore W2000206525C54355233 @default.
- W2000206525 hasConceptScore W2000206525C71924100 @default.
- W2000206525 hasConceptScore W2000206525C74172505 @default.
- W2000206525 hasConceptScore W2000206525C86803240 @default.
- W2000206525 hasLocation W20002065251 @default.
- W2000206525 hasOpenAccess W2000206525 @default.
- W2000206525 hasPrimaryLocation W20002065251 @default.
- W2000206525 hasRelatedWork W1509393062 @default.
- W2000206525 hasRelatedWork W1964165089 @default.
- W2000206525 hasRelatedWork W1974147340 @default.
- W2000206525 hasRelatedWork W1985715079 @default.
- W2000206525 hasRelatedWork W2010091924 @default.
- W2000206525 hasRelatedWork W2015524556 @default.
- W2000206525 hasRelatedWork W2018156901 @default.
- W2000206525 hasRelatedWork W2018324986 @default.
- W2000206525 hasRelatedWork W2021038572 @default.
- W2000206525 hasRelatedWork W2042431351 @default.
- W2000206525 hasRelatedWork W2061413904 @default.
- W2000206525 hasRelatedWork W2080280022 @default.
- W2000206525 hasRelatedWork W2082171029 @default.
- W2000206525 hasRelatedWork W2145388421 @default.
- W2000206525 hasRelatedWork W2208906432 @default.
- W2000206525 hasRelatedWork W2385271903 @default.
- W2000206525 hasRelatedWork W2462826840 @default.
- W2000206525 hasRelatedWork W2771347580 @default.
- W2000206525 hasRelatedWork W3036651405 @default.
- W2000206525 hasRelatedWork W2331817580 @default.
- W2000206525 isParatext "false" @default.
- W2000206525 isRetracted "false" @default.
- W2000206525 magId "2000206525" @default.
- W2000206525 workType "article" @default.