FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000215101> ?p ?o ?g. }

• W2000215101 endingPage "25" @default.
• W2000215101 startingPage "14" @default.
• W2000215101 abstract "Sex steroids can influence developmental processes and support the survival of neurons in the embryonic central nervous system. Recent studies have shown that estrogen receptors are also expressed in the peripheral nervous system, in the dorsal root ganglia (DRG) of chick embryos. However, no studies have examined the effects of sex steroids on development of embryonic DRG. In the present study, 0.2 microg, 1.0 microg, 5.0 microg 10 microg, 20 microg, 25 microg, and 40 microg doses of testosterone or estradiol were delivered to chick embryos at Hamburger and Hamilton stage 18 (E3). The actions of these doses of sex steroids on the development of the C5DRG (fifth cervical ganglion, a normal DRG) and C2DRG (a transient ganglion known as a Froriep's DRG) were then evaluated by quantifying ganglionic volumes, cell number, proliferation, and apoptosis after 1 day of growth to stage 23. We found that both testosterone and estradiol promoted proliferation of cells in both normal DRG and the Froriep's ganglia. By contrast, estradiol significantly increased the number of apoptotic cells, while testosterone strongly inhibited apoptosis. These actions of sex steroids on DRG development were dose-dependent, and C5DRG and C2DRG showed different sensitivities to the applied sex steroids. In addition, the present results demonstrated that specific ER and AR inhibitors (tamoxifen and flutamide) did not influence the effects of 5 microg E2 and 5 microg T on C2 and C5DRG significantly. These results demonstrate that male and female sex steroids can modulate DRG development through an epigenetic mechanism, as had been shown for the central nervous system." @default.
• W2000215101 created "2016-06-24" @default.
• W2000215101 creator A5003322678 @default.
• W2000215101 creator A5011274098 @default.
• W2000215101 creator A5057012556 @default.
• W2000215101 creator A5084376477 @default.
• W2000215101 date "2005-03-01" @default.
• W2000215101 modified "2023-10-16" @default.
• W2000215101 title "Effects of male and female sex steroids on the development of normal and the transient Froriep's dorsal root ganglia of the chick embryo" @default.
• W2000215101 cites W1644922490 @default.
• W2000215101 cites W1761997414 @default.
• W2000215101 cites W1867290056 @default.
• W2000215101 cites W1903028880 @default.
• W2000215101 cites W1964726163 @default.
• W2000215101 cites W1964902982 @default.
• W2000215101 cites W1966104245 @default.
• W2000215101 cites W1974638429 @default.
• W2000215101 cites W1974730873 @default.
• W2000215101 cites W1975302145 @default.
• W2000215101 cites W1976149078 @default.
• W2000215101 cites W1980060180 @default.
• W2000215101 cites W1985354237 @default.
• W2000215101 cites W1985496531 @default.
• W2000215101 cites W1986291439 @default.
• W2000215101 cites W1990735007 @default.
• W2000215101 cites W1991692440 @default.
• W2000215101 cites W1992862338 @default.
• W2000215101 cites W1994874098 @default.
• W2000215101 cites W2000744975 @default.
• W2000215101 cites W2002673255 @default.
• W2000215101 cites W2006268333 @default.
• W2000215101 cites W2007496805 @default.
• W2000215101 cites W2007547464 @default.
• W2000215101 cites W2017772219 @default.
• W2000215101 cites W2022406587 @default.
• W2000215101 cites W2026455181 @default.
• W2000215101 cites W2030564926 @default.
• W2000215101 cites W2042411910 @default.
• W2000215101 cites W2054112137 @default.
• W2000215101 cites W2054955320 @default.
• W2000215101 cites W2054976129 @default.
• W2000215101 cites W2056083446 @default.
• W2000215101 cites W2058389392 @default.
• W2000215101 cites W2076405008 @default.
• W2000215101 cites W2083496235 @default.
• W2000215101 cites W2113955611 @default.
• W2000215101 cites W2116558451 @default.
• W2000215101 cites W2128496504 @default.
• W2000215101 cites W2138099863 @default.
• W2000215101 cites W2140034535 @default.
• W2000215101 cites W2142614790 @default.
• W2000215101 cites W2154745705 @default.
• W2000215101 cites W2260755944 @default.
• W2000215101 cites W4229685353 @default.
• W2000215101 cites W4317563605 @default.
• W2000215101 cites W4320573465 @default.
• W2000215101 doi "https://doi.org/10.1016/j.devbrainres.2004.12.001" @default.
• W2000215101 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15763271" @default.
• W2000215101 hasPublicationYear "2005" @default.
• W2000215101 type Work @default.
• W2000215101 sameAs 2000215101 @default.
• W2000215101 citedByCount "8" @default.
• W2000215101 countsByYear W20002151012020 @default.
• W2000215101 crossrefType "journal-article" @default.
• W2000215101 hasAuthorship W2000215101A5003322678 @default.
• W2000215101 hasAuthorship W2000215101A5011274098 @default.
• W2000215101 hasAuthorship W2000215101A5057012556 @default.
• W2000215101 hasAuthorship W2000215101A5084376477 @default.
• W2000215101 hasConcept C104317684 @default.
• W2000215101 hasConcept C105702510 @default.
• W2000215101 hasConcept C121608353 @default.
• W2000215101 hasConcept C126322002 @default.
• W2000215101 hasConcept C134018914 @default.
• W2000215101 hasConcept C140530291 @default.
• W2000215101 hasConcept C196843134 @default.
• W2000215101 hasConcept C2776281502 @default.
• W2000215101 hasConcept C2777164284 @default.
• W2000215101 hasConcept C2778313021 @default.
• W2000215101 hasConcept C2779279991 @default.
• W2000215101 hasConcept C2780192828 @default.
• W2000215101 hasConcept C2781142105 @default.
• W2000215101 hasConcept C55493867 @default.
• W2000215101 hasConcept C61367390 @default.
• W2000215101 hasConcept C63405245 @default.
• W2000215101 hasConcept C71924100 @default.
• W2000215101 hasConcept C86803240 @default.
• W2000215101 hasConcept C87073359 @default.
• W2000215101 hasConcept C95444343 @default.
• W2000215101 hasConceptScore W2000215101C104317684 @default.
• W2000215101 hasConceptScore W2000215101C105702510 @default.
• W2000215101 hasConceptScore W2000215101C121608353 @default.
• W2000215101 hasConceptScore W2000215101C126322002 @default.
• W2000215101 hasConceptScore W2000215101C134018914 @default.
• W2000215101 hasConceptScore W2000215101C140530291 @default.
• W2000215101 hasConceptScore W2000215101C196843134 @default.
• W2000215101 hasConceptScore W2000215101C2776281502 @default.
• W2000215101 hasConceptScore W2000215101C2777164284 @default.
• W2000215101 hasConceptScore W2000215101C2778313021 @default.

• next