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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000215535> ?p ?o ?g. }

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• W2000215535 startingPage "1931" @default.
• W2000215535 abstract "Two methods to produce (2S)-5-amino-2-(1-n-propyl-1H-imidazol-4-ylmethyl)-pentanoic acid were investigated. Diastereoisomeric salt resolution, using the quinidine salt, gave the desired intermediate in 98% ee and 33% yield. Asymmetric hydrogenation of various substrates gave high conversions, with up to 83% ee. Integration of these two approaches via asymmetric hydrogenation of a quinidine salt substrate followed by crystallization provided the desired intermediate in 94% ee and 76% yield." @default.
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• W2000215535 date "2005-04-20" @default.
• W2000215535 modified "2023-09-26" @default.
• W2000215535 title "Efficient Synthesis of an Imidazole-Substituted δ-Amino Acid by the Integration of Chiral Technologies" @default.
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• W2000215535 doi "https://doi.org/10.1021/ol0503081" @default.
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