FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000216893> ?p ?o ?g. }

• W2000216893 endingPage "291" @default.
• W2000216893 startingPage "281" @default.
• W2000216893 abstract "The reaction kinetics of radioadaptive response of low doses of X-rays have been studied in quiescent cultured mouse cells. Mouse m5S cells pre-exposed in G1 to low doses of X-rays became insensitive to the induction of chromosome aberrations, mutation toward 6-thioguanine resistance, and cell killing. Adapted cells were, however, more susceptible to morphological transformation by subsequent high challenging doses of X-rays. The cytogenetic adaptation, which lasted about 20 h pertained to a narrow dose range. X-ray doses below and above 0·1 Gy appeared to be recognized as different signals; higher doses of X-rays were incapable of inducing adaptation and rapidly extinguished the adapted condition. Treatment with 12-O-tetradecanoyl-phorbol 13-acetate (TPA) and hydrogen peroxide, but not the xanthine/xanthine oxidase superoxide-generating system, mimicked X-rays in inducing adaptation when applied at low doses. Over-exposure to TPA or inhibitors of protein kinase C (PKC) abrogated the adaptive response to X-rays, providing evidence for the involvement of a PKC-mediated signalling pathway. The lack of radioadaptive response in a tumorigenic variant, clone 6110, and its restoration in the morphological revertant obtained by introducing human chromosome 11 further suggested that interference of signalling pathways may alter radioadaptive responses in malignant cells." @default.
• W2000216893 created "2016-06-24" @default.
• W2000216893 creator A5067788481 @default.
• W2000216893 date "1995-01-01" @default.
• W2000216893 modified "2023-09-23" @default.
• W2000216893 title "On the Reaction Kinetics of the Radioadaptive Response in Cultured Mouse Cells" @default.
• W2000216893 cites W1594758412 @default.
• W2000216893 cites W1967268473 @default.
• W2000216893 cites W1972195403 @default.
• W2000216893 cites W1973454785 @default.
• W2000216893 cites W1973568385 @default.
• W2000216893 cites W1976423026 @default.
• W2000216893 cites W1978863345 @default.
• W2000216893 cites W1985177188 @default.
• W2000216893 cites W1993282564 @default.
• W2000216893 cites W1995652838 @default.
• W2000216893 cites W2000436007 @default.
• W2000216893 cites W2001692359 @default.
• W2000216893 cites W2005803011 @default.
• W2000216893 cites W2007546437 @default.
• W2000216893 cites W2010409226 @default.
• W2000216893 cites W2010429822 @default.
• W2000216893 cites W2014503028 @default.
• W2000216893 cites W2015161802 @default.
• W2000216893 cites W2023954352 @default.
• W2000216893 cites W2028614554 @default.
• W2000216893 cites W2031327521 @default.
• W2000216893 cites W2035852033 @default.
• W2000216893 cites W2036488022 @default.
• W2000216893 cites W2036744157 @default.
• W2000216893 cites W2039109181 @default.
• W2000216893 cites W2051902571 @default.
• W2000216893 cites W2057704001 @default.
• W2000216893 cites W2059760067 @default.
• W2000216893 cites W2060254674 @default.
• W2000216893 cites W2061413359 @default.
• W2000216893 cites W2061900377 @default.
• W2000216893 cites W2062039330 @default.
• W2000216893 cites W2065659070 @default.
• W2000216893 cites W2075473225 @default.
• W2000216893 cites W2084491525 @default.
• W2000216893 cites W2086310749 @default.
• W2000216893 cites W2087266097 @default.
• W2000216893 cites W2089787294 @default.
• W2000216893 cites W2091044359 @default.
• W2000216893 cites W2093863618 @default.
• W2000216893 cites W2094872845 @default.
• W2000216893 cites W2112027230 @default.
• W2000216893 cites W2121080583 @default.
• W2000216893 cites W2132000251 @default.
• W2000216893 cites W2138550860 @default.
• W2000216893 cites W2142339245 @default.
• W2000216893 cites W2148200181 @default.
• W2000216893 cites W2151058265 @default.
• W2000216893 cites W2156305838 @default.
• W2000216893 cites W2158293301 @default.
• W2000216893 cites W2160733363 @default.
• W2000216893 cites W2317158825 @default.
• W2000216893 doi "https://doi.org/10.1080/09553009514551211" @default.
• W2000216893 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7561388" @default.
• W2000216893 hasPublicationYear "1995" @default.
• W2000216893 type Work @default.
• W2000216893 sameAs 2000216893 @default.
• W2000216893 citedByCount "105" @default.
• W2000216893 countsByYear W20002168932012 @default.
• W2000216893 countsByYear W20002168932013 @default.
• W2000216893 countsByYear W20002168932014 @default.
• W2000216893 countsByYear W20002168932015 @default.
• W2000216893 countsByYear W20002168932016 @default.
• W2000216893 countsByYear W20002168932017 @default.
• W2000216893 countsByYear W20002168932018 @default.
• W2000216893 countsByYear W20002168932019 @default.
• W2000216893 countsByYear W20002168932020 @default.
• W2000216893 countsByYear W20002168932022 @default.
• W2000216893 crossrefType "journal-article" @default.
• W2000216893 hasAuthorship W2000216893A5067788481 @default.
• W2000216893 hasConcept C153911025 @default.
• W2000216893 hasConcept C181199279 @default.
• W2000216893 hasConcept C184235292 @default.
• W2000216893 hasConcept C185592680 @default.
• W2000216893 hasConcept C195794163 @default.
• W2000216893 hasConcept C2778102346 @default.
• W2000216893 hasConcept C2780795997 @default.
• W2000216893 hasConcept C502942594 @default.
• W2000216893 hasConcept C55493867 @default.
• W2000216893 hasConcept C86803240 @default.
• W2000216893 hasConcept C95444343 @default.
• W2000216893 hasConcept C98274493 @default.
• W2000216893 hasConceptScore W2000216893C153911025 @default.
• W2000216893 hasConceptScore W2000216893C181199279 @default.
• W2000216893 hasConceptScore W2000216893C184235292 @default.
• W2000216893 hasConceptScore W2000216893C185592680 @default.
• W2000216893 hasConceptScore W2000216893C195794163 @default.
• W2000216893 hasConceptScore W2000216893C2778102346 @default.
• W2000216893 hasConceptScore W2000216893C2780795997 @default.
• W2000216893 hasConceptScore W2000216893C502942594 @default.
• W2000216893 hasConceptScore W2000216893C55493867 @default.
• W2000216893 hasConceptScore W2000216893C86803240 @default.

• next