Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000220767> ?p ?o ?g. }
- W2000220767 abstract "Abstract Background. Penetrating wounds with environmental contamination are associated with a range of infectious complications, including fungus. This is the first study to examine the epidemiology, resistance patterns, and outcomes of Candida infections and colonization in United States military patients injured in Iraq and Afghanistan. Methods. Clinical information associated with initial unique and serial Candida isolates collected from patients (June 2009–October 2013) through the Trauma Infectious Disease Outcomes Study (TIDOS) was evaluated. Susceptibilities were performed using Sensititre YeastOne (YO-9) plates and interpreted by Clinical Laboratory and Standards Institute (CLSI) and adjusted-European Committee on Antimicrobial Susceptibility Testing (EUCAST) criteria. Results. The analysis included 127 patients with 131 unique Candida isolates, of which 102 were Candida albicans and 29 non-albicans Candida spp. Overall, 99% of patients were male with a median age of 23 and an injury severity score of 22. Injuries were primarily due to blasts (77%) and sustained among personnel serving in Afghanistan (89%). There was a median of 7 days from injury to Candida isolation, and 74 isolates were associated with infection. In the multivariate analysis, non-albicans Candida spp were associated with prior antifungal exposure, blood isolates, and wound isolates (P < .01). Nonsusceptibility by CLSI and EUCAST criteria was associated with non-albicans Candida spp (P < .05). Patients with Candida isolation had a 7.1% mortality rate, compared with 1.4% from the overall TIDOS population. Conclusions. Candida isolation from patients with penetrating war injuries may identify a population at higher risk for death. Prospective studies are needed to determine whether targeted antifungals and surgical management will affect this mortality rate." @default.
- W2000220767 created "2016-06-24" @default.
- W2000220767 creator A5010496694 @default.
- W2000220767 creator A5010964673 @default.
- W2000220767 creator A5011771274 @default.
- W2000220767 creator A5028590386 @default.
- W2000220767 creator A5051297695 @default.
- W2000220767 creator A5051587699 @default.
- W2000220767 creator A5065407640 @default.
- W2000220767 creator A5077762762 @default.
- W2000220767 creator A5087034786 @default.
- W2000220767 date "2014-01-01" @default.
- W2000220767 modified "2023-10-17" @default.
- W2000220767 title "Resistance Patterns and Clinical Significance of Candida Colonization and Infection in Combat-Related Injured Patients From Iraq and Afghanistan" @default.
- W2000220767 cites W12653918 @default.
- W2000220767 cites W1519461937 @default.
- W2000220767 cites W1844236389 @default.
- W2000220767 cites W1887118 @default.
- W2000220767 cites W1900369848 @default.
- W2000220767 cites W1969453606 @default.
- W2000220767 cites W1973642271 @default.
- W2000220767 cites W1979531469 @default.
- W2000220767 cites W1993526036 @default.
- W2000220767 cites W1998771714 @default.
- W2000220767 cites W2010445536 @default.
- W2000220767 cites W2017430996 @default.
- W2000220767 cites W2023601006 @default.
- W2000220767 cites W2025493130 @default.
- W2000220767 cites W2031358349 @default.
- W2000220767 cites W2033599332 @default.
- W2000220767 cites W2052843476 @default.
- W2000220767 cites W2062983075 @default.
- W2000220767 cites W2073315399 @default.
- W2000220767 cites W2081795627 @default.
- W2000220767 cites W2094730521 @default.
- W2000220767 cites W2117643625 @default.
- W2000220767 cites W2118836068 @default.
- W2000220767 cites W2125338058 @default.
- W2000220767 cites W2129528166 @default.
- W2000220767 cites W2132783048 @default.
- W2000220767 cites W2135265373 @default.
- W2000220767 cites W2136514143 @default.
- W2000220767 cites W2138866758 @default.
- W2000220767 cites W2141586948 @default.
- W2000220767 cites W2143623054 @default.
- W2000220767 cites W2156267021 @default.
- W2000220767 cites W2163430123 @default.
- W2000220767 cites W2166734004 @default.
- W2000220767 cites W2169835699 @default.
- W2000220767 cites W2316580455 @default.
- W2000220767 doi "https://doi.org/10.1093/ofid/ofu109" @default.
- W2000220767 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4324214" @default.
- W2000220767 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25734177" @default.
- W2000220767 hasPublicationYear "2014" @default.
- W2000220767 type Work @default.
- W2000220767 sameAs 2000220767 @default.
- W2000220767 citedByCount "11" @default.
- W2000220767 countsByYear W20002207672016 @default.
- W2000220767 countsByYear W20002207672017 @default.
- W2000220767 countsByYear W20002207672018 @default.
- W2000220767 countsByYear W20002207672019 @default.
- W2000220767 countsByYear W20002207672021 @default.
- W2000220767 countsByYear W20002207672022 @default.
- W2000220767 crossrefType "journal-article" @default.
- W2000220767 hasAuthorship W2000220767A5010496694 @default.
- W2000220767 hasAuthorship W2000220767A5010964673 @default.
- W2000220767 hasAuthorship W2000220767A5011771274 @default.
- W2000220767 hasAuthorship W2000220767A5028590386 @default.
- W2000220767 hasAuthorship W2000220767A5051297695 @default.
- W2000220767 hasAuthorship W2000220767A5051587699 @default.
- W2000220767 hasAuthorship W2000220767A5065407640 @default.
- W2000220767 hasAuthorship W2000220767A5077762762 @default.
- W2000220767 hasAuthorship W2000220767A5087034786 @default.
- W2000220767 hasBestOaLocation W20002207671 @default.
- W2000220767 hasConcept C107130276 @default.
- W2000220767 hasConcept C114851261 @default.
- W2000220767 hasConcept C126322002 @default.
- W2000220767 hasConcept C2775941552 @default.
- W2000220767 hasConcept C2776927270 @default.
- W2000220767 hasConcept C2780917455 @default.
- W2000220767 hasConcept C2908647359 @default.
- W2000220767 hasConcept C2992965680 @default.
- W2000220767 hasConcept C71924100 @default.
- W2000220767 hasConcept C86803240 @default.
- W2000220767 hasConcept C89423630 @default.
- W2000220767 hasConcept C99454951 @default.
- W2000220767 hasConceptScore W2000220767C107130276 @default.
- W2000220767 hasConceptScore W2000220767C114851261 @default.
- W2000220767 hasConceptScore W2000220767C126322002 @default.
- W2000220767 hasConceptScore W2000220767C2775941552 @default.
- W2000220767 hasConceptScore W2000220767C2776927270 @default.
- W2000220767 hasConceptScore W2000220767C2780917455 @default.
- W2000220767 hasConceptScore W2000220767C2908647359 @default.
- W2000220767 hasConceptScore W2000220767C2992965680 @default.
- W2000220767 hasConceptScore W2000220767C71924100 @default.
- W2000220767 hasConceptScore W2000220767C86803240 @default.
- W2000220767 hasConceptScore W2000220767C89423630 @default.
- W2000220767 hasConceptScore W2000220767C99454951 @default.
- W2000220767 hasIssue "3" @default.
- W2000220767 hasLocation W20002207671 @default.