Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000221008> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2000221008 endingPage "1121" @default.
- W2000221008 startingPage "1111" @default.
- W2000221008 abstract "1. Microsomal monooxygenase systems which contain cytochrome P-450 forms as their active centres are found in birds, reptiles and amphibians. Liver provides a rich source of monooxygenases but they are also present in other tissues.2. In the hepatic microsomes of these species, levels of cytochrome P-450 and, in most cases monooxygenase activities, are lower than are found in hepatic microsomes of mammals.3. Amongst birds, the lowest hepatic microsomal monooxygenase activities have been reported for specialized predators (fish-eaters and raptors).4. When birds are dosed with inducers of the 3-methylcholanthrene (MC) type, the pattern of induction is similar to that in mammals. In contrast, phenobarbitone-type inducers are less effective in birds than in mammals—in some cases having no action at all. Prochloraz is a stronger inducer in birds than in the rat; it is an inducer of mixed type in birds.5. Partial purification of avian cytochromes P-450 indicates substantial differences in properties from those of mammals. Further differences between birds and mammals in regard to the immunochemical properties of isoforms are evident from comparative studies using Western blotting.6. On the evidence of Western blotting and response to inducers, cytochromes of family II (P450 II) seem less well represented in birds than in mammals.7. The low monooxygenase activities of certain species of birds may make them relatively susceptible to lipophilic environmental chemicals that are detoxified by this system." @default.
- W2000221008 created "2016-06-24" @default.
- W2000221008 creator A5041753848 @default.
- W2000221008 creator A5050857564 @default.
- W2000221008 date "1989-01-01" @default.
- W2000221008 modified "2023-10-16" @default.
- W2000221008 title "The monooxygenases of birds, reptiles and amphibians" @default.
- W2000221008 cites W1871379037 @default.
- W2000221008 cites W1938877388 @default.
- W2000221008 cites W2024632469 @default.
- W2000221008 cites W2024986743 @default.
- W2000221008 cites W2028108082 @default.
- W2000221008 cites W2031429717 @default.
- W2000221008 cites W2046327369 @default.
- W2000221008 cites W2049567684 @default.
- W2000221008 cites W2049772668 @default.
- W2000221008 cites W2059042007 @default.
- W2000221008 cites W2080492214 @default.
- W2000221008 cites W2132927623 @default.
- W2000221008 cites W2191498793 @default.
- W2000221008 cites W2072758187 @default.
- W2000221008 doi "https://doi.org/10.3109/00498258909043165" @default.
- W2000221008 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2683412" @default.
- W2000221008 hasPublicationYear "1989" @default.
- W2000221008 type Work @default.
- W2000221008 sameAs 2000221008 @default.
- W2000221008 citedByCount "76" @default.
- W2000221008 countsByYear W20002210082012 @default.
- W2000221008 countsByYear W20002210082013 @default.
- W2000221008 countsByYear W20002210082016 @default.
- W2000221008 countsByYear W20002210082017 @default.
- W2000221008 countsByYear W20002210082018 @default.
- W2000221008 countsByYear W20002210082019 @default.
- W2000221008 countsByYear W20002210082020 @default.
- W2000221008 countsByYear W20002210082021 @default.
- W2000221008 countsByYear W20002210082022 @default.
- W2000221008 countsByYear W20002210082023 @default.
- W2000221008 crossrefType "journal-article" @default.
- W2000221008 hasAuthorship W2000221008A5041753848 @default.
- W2000221008 hasAuthorship W2000221008A5050857564 @default.
- W2000221008 hasConcept C104317684 @default.
- W2000221008 hasConcept C115448650 @default.
- W2000221008 hasConcept C119795356 @default.
- W2000221008 hasConcept C13002179 @default.
- W2000221008 hasConcept C132154277 @default.
- W2000221008 hasConcept C181199279 @default.
- W2000221008 hasConcept C2225953 @default.
- W2000221008 hasConcept C2778307567 @default.
- W2000221008 hasConcept C2780768313 @default.
- W2000221008 hasConcept C526171541 @default.
- W2000221008 hasConcept C55493867 @default.
- W2000221008 hasConcept C86803240 @default.
- W2000221008 hasConcept C87644729 @default.
- W2000221008 hasConcept C90856448 @default.
- W2000221008 hasConceptScore W2000221008C104317684 @default.
- W2000221008 hasConceptScore W2000221008C115448650 @default.
- W2000221008 hasConceptScore W2000221008C119795356 @default.
- W2000221008 hasConceptScore W2000221008C13002179 @default.
- W2000221008 hasConceptScore W2000221008C132154277 @default.
- W2000221008 hasConceptScore W2000221008C181199279 @default.
- W2000221008 hasConceptScore W2000221008C2225953 @default.
- W2000221008 hasConceptScore W2000221008C2778307567 @default.
- W2000221008 hasConceptScore W2000221008C2780768313 @default.
- W2000221008 hasConceptScore W2000221008C526171541 @default.
- W2000221008 hasConceptScore W2000221008C55493867 @default.
- W2000221008 hasConceptScore W2000221008C86803240 @default.
- W2000221008 hasConceptScore W2000221008C87644729 @default.
- W2000221008 hasConceptScore W2000221008C90856448 @default.
- W2000221008 hasIssue "10" @default.
- W2000221008 hasLocation W20002210081 @default.
- W2000221008 hasLocation W20002210082 @default.
- W2000221008 hasOpenAccess W2000221008 @default.
- W2000221008 hasPrimaryLocation W20002210081 @default.
- W2000221008 hasRelatedWork W1990154119 @default.
- W2000221008 hasRelatedWork W1992175309 @default.
- W2000221008 hasRelatedWork W1993548647 @default.
- W2000221008 hasRelatedWork W2000871663 @default.
- W2000221008 hasRelatedWork W2023628640 @default.
- W2000221008 hasRelatedWork W2044847788 @default.
- W2000221008 hasRelatedWork W2057088712 @default.
- W2000221008 hasRelatedWork W2063675428 @default.
- W2000221008 hasRelatedWork W2415344523 @default.
- W2000221008 hasRelatedWork W2473476752 @default.
- W2000221008 hasVolume "19" @default.
- W2000221008 isParatext "false" @default.
- W2000221008 isRetracted "false" @default.
- W2000221008 magId "2000221008" @default.
- W2000221008 workType "article" @default.