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• W2000221561 abstract "An in vitro transcription system for the tryptophan operon of Escherichia coli was used to determine the mechanism by which trp† repressor inhibits transcription of the operon. It was found that trp repressor-binding prevents binding of RNA polymerase to the operon. It was also observed that when polymerase is prebound to the trp promoter, repressor cannot prevent it from transcribing. These results suggest the existence of a functional overlap between trp promoter and trp operator regions and indicate that repressor acts by preventing RNA polymerase attachment to the promoter region of the operon." @default.
• W2000221561 created "2016-06-24" @default.
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• W2000221561 date "1975-02-01" @default.
• W2000221561 modified "2023-10-16" @default.
• W2000221561 title "Interaction of the trp repressor and RNA polymerase with the trp operon" @default.
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• W2000221561 doi "https://doi.org/10.1016/0022-2836(75)90093-5" @default.
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