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- W2000222177 abstract "The Human Genome Project has completed a successful three-year pilot project that has resulted in 280 875 kb of accurate, non-redundant human genomic sequence data being deposited in the public database (about 9% of the genome, shown graphically in Fig. 1). Recently, it has been announced that, as a first step towards accelerated completion of the genome, a ‘working draft’ sequence will be produced early in 2000 that will account for about 90% of the approximately three billion total bases 1 Pennisi E. Academic sequencers challenge Celera in sprint to the finish. Science. 1999; 283: 1822-1823 Crossref PubMed Scopus (24) Google Scholar . This strategy might be likened to the authoring of a book – an initial working draft will be produced, followed by cycles of revisions in which details are added and errors corrected, ultimately leading to the final reference work. While it will be interesting to watch the developments in this fast-paced field over the next year or two, the practical benefit for most of us is the fact that huge amounts of DNA sequence will be pouring into the public databases. It is important for researchers to have early access to the genome because of its tremendous potential for accelerating biomedical research. We have developed an Internet resource (www.ncbi.nlm.nih.gov/genome/seq) to help make effective use of these data, by providing a simple means of browsing and searching of the data, together with background information and an assessment of overall sequencing progress." @default.
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- W2000222177 date "1999-07-01" @default.
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- W2000222177 title "Making effective use of human genomic sequence data" @default.
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- W2000222177 doi "https://doi.org/10.1016/s0168-9525(99)01762-x" @default.
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