FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000226222> ?p ?o ?g. }

• W2000226222 endingPage "96" @default.
• W2000226222 startingPage "87" @default.
• W2000226222 abstract "The contractile nature of porcine pancreatic phospholipase A2 (PLA2) was characterized on paired pleural strips obtained from guinea pig lung. PLA2 (0.003-10 U/ml) produced concentration-related contractile responses which were sensitive to various drugs. The major component of the PLA2-induced contractions was derived from products of the cyclooxygenase pathway since a cyclooxygenase inhibitor or the combination of a thromboxane synthetase inhibitor and a thromboxane receptor antagonist produced a 54-65% reduction of the contractile responses. 5-Lipoxygenase products contributed to a smaller component of the PLA2-induced responses since 5-lipoxygenase inhibitors or the combination of a leukotriene (LT) B4 receptor antagonist and an LTD4/LTE4 receptor antagonist only suppressed the maximal responses 22-32%. PLA2-induced contractile responses were nearly abolished by altering both sides of the arachidonic acid cascade simultaneously. In contrast, a PAF receptor antagonist, a histamine (H1) receptor antagonist and an acetylcholine receptor antagonist, failed to significantly reduce PLA2-induced responses. These results demonstrate that exogenous administration of porcine pancreatic PLA2 produced concentration-dependent contractions of pleural strips mediated through the generation of eicosanoids." @default.
• W2000226222 created "2016-06-24" @default.
• W2000226222 creator A5049086194 @default.
• W2000226222 creator A5055565961 @default.
• W2000226222 creator A5064788120 @default.
• W2000226222 creator A5077563647 @default.
• W2000226222 date "1992-05-01" @default.
• W2000226222 modified "2023-09-27" @default.
• W2000226222 title "Porcine pancreatic phospholipase A2-induced contractions of guinea pig lung pleural strips" @default.
• W2000226222 cites W1977989290 @default.
• W2000226222 cites W1980811486 @default.
• W2000226222 cites W1984930783 @default.
• W2000226222 cites W1986462191 @default.
• W2000226222 cites W1987056475 @default.
• W2000226222 cites W1993378893 @default.
• W2000226222 cites W1996417833 @default.
• W2000226222 cites W2011192101 @default.
• W2000226222 cites W2015572460 @default.
• W2000226222 cites W2020391975 @default.
• W2000226222 cites W2031640024 @default.
• W2000226222 cites W2035162961 @default.
• W2000226222 cites W2053329862 @default.
• W2000226222 cites W2059727135 @default.
• W2000226222 cites W2068403853 @default.
• W2000226222 cites W2073266009 @default.
• W2000226222 cites W2117562256 @default.
• W2000226222 cites W2265143763 @default.
• W2000226222 cites W29839821 @default.
• W2000226222 doi "https://doi.org/10.1016/0014-2999(92)90213-n" @default.
• W2000226222 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1526256" @default.
• W2000226222 hasPublicationYear "1992" @default.
• W2000226222 type Work @default.
• W2000226222 sameAs 2000226222 @default.
• W2000226222 citedByCount "40" @default.
• W2000226222 countsByYear W20002262222023 @default.
• W2000226222 crossrefType "journal-article" @default.
• W2000226222 hasAuthorship W2000226222A5049086194 @default.
• W2000226222 hasAuthorship W2000226222A5055565961 @default.
• W2000226222 hasAuthorship W2000226222A5064788120 @default.
• W2000226222 hasAuthorship W2000226222A5077563647 @default.
• W2000226222 hasConcept C126322002 @default.
• W2000226222 hasConcept C134018914 @default.
• W2000226222 hasConcept C170493617 @default.
• W2000226222 hasConcept C181199279 @default.
• W2000226222 hasConcept C185592680 @default.
• W2000226222 hasConcept C2776042228 @default.
• W2000226222 hasConcept C2776452501 @default.
• W2000226222 hasConcept C2776551241 @default.
• W2000226222 hasConcept C2776785769 @default.
• W2000226222 hasConcept C2776885963 @default.
• W2000226222 hasConcept C2778078955 @default.
• W2000226222 hasConcept C2778122271 @default.
• W2000226222 hasConcept C2778815084 @default.
• W2000226222 hasConcept C2779689624 @default.
• W2000226222 hasConcept C2781024287 @default.
• W2000226222 hasConcept C55493867 @default.
• W2000226222 hasConcept C71924100 @default.
• W2000226222 hasConcept C86803240 @default.
• W2000226222 hasConcept C89560881 @default.
• W2000226222 hasConcept C98274493 @default.
• W2000226222 hasConceptScore W2000226222C126322002 @default.
• W2000226222 hasConceptScore W2000226222C134018914 @default.
• W2000226222 hasConceptScore W2000226222C170493617 @default.
• W2000226222 hasConceptScore W2000226222C181199279 @default.
• W2000226222 hasConceptScore W2000226222C185592680 @default.
• W2000226222 hasConceptScore W2000226222C2776042228 @default.
• W2000226222 hasConceptScore W2000226222C2776452501 @default.
• W2000226222 hasConceptScore W2000226222C2776551241 @default.
• W2000226222 hasConceptScore W2000226222C2776785769 @default.
• W2000226222 hasConceptScore W2000226222C2776885963 @default.
• W2000226222 hasConceptScore W2000226222C2778078955 @default.
• W2000226222 hasConceptScore W2000226222C2778122271 @default.
• W2000226222 hasConceptScore W2000226222C2778815084 @default.
• W2000226222 hasConceptScore W2000226222C2779689624 @default.
• W2000226222 hasConceptScore W2000226222C2781024287 @default.
• W2000226222 hasConceptScore W2000226222C55493867 @default.
• W2000226222 hasConceptScore W2000226222C71924100 @default.
• W2000226222 hasConceptScore W2000226222C86803240 @default.
• W2000226222 hasConceptScore W2000226222C89560881 @default.
• W2000226222 hasConceptScore W2000226222C98274493 @default.
• W2000226222 hasIssue "1" @default.
• W2000226222 hasLocation W20002262221 @default.
• W2000226222 hasLocation W20002262222 @default.
• W2000226222 hasOpenAccess W2000226222 @default.
• W2000226222 hasPrimaryLocation W20002262221 @default.
• W2000226222 hasRelatedWork W1823383841 @default.
• W2000226222 hasRelatedWork W2000226222 @default.
• W2000226222 hasRelatedWork W2023961140 @default.
• W2000226222 hasRelatedWork W2024047304 @default.
• W2000226222 hasRelatedWork W2026574739 @default.
• W2000226222 hasRelatedWork W2035508095 @default.
• W2000226222 hasRelatedWork W2063176859 @default.
• W2000226222 hasRelatedWork W2065482443 @default.
• W2000226222 hasRelatedWork W2230503133 @default.
• W2000226222 hasRelatedWork W2418358272 @default.
• W2000226222 hasVolume "216" @default.
• W2000226222 isParatext "false" @default.
• W2000226222 isRetracted "false" @default.

• next