Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000231382> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2000231382 endingPage "102" @default.
- W2000231382 startingPage "96" @default.
- W2000231382 abstract "Plasma phosphate values are significantly lower in spontaneously hypertensive rats (SHR) than in normotensive Wistar-Kyoto rats (WKY). In this study, we increased plasma phosphate in SHR by a dietary phosphate intake and followed the effects on blood pressure. Fifteen male WKY and 15 male SHR were housed from 4 weeks of age up to 26 weeks. At 4 weeks of age all SHR manifested a hypophosphatemia compared with age-matched WKY (F = 62, p less than 0.0003). At 5 weeks of age, the rats were divided into three diet groups: a control group, a group receiving 1.41% (wt/vol) KCl in drinking water, and a group receiving 2% (wt/vol) K2HPO4 X KH2PO4 in drinking water. In the control (F = 16.2, p less than 0.02) and KCl groups, (F = 36.3, p less than 0.03), hypophosphatemia persisted throughout the study. The phosphate-supplemented diet normalized plasma phosphate level in SHR but did not change plasma phosphate level in WKY. As a consequence, no difference in plasma phosphate level between WKY and SHR was present in the group receiving additional phosphate from that time on (F = 1.2, p greater than 0.41). The phosphate-supplemented diet significantly decreased systolic blood pressure in both strains. In phosphate-supplemented SHR, a significant decline in systolic blood pressure was observed from 20 weeks of age on (at 20 weeks of age: 222 +/- 3 mm Hg for control SHR vs 198 +/- 5 mm Hg for phosphate-supplemented SHR; p less than 0.0003).(ABSTRACT TRUNCATED AT 250 WORDS)" @default.
- W2000231382 created "2016-06-24" @default.
- W2000231382 creator A5009397682 @default.
- W2000231382 creator A5033276783 @default.
- W2000231382 creator A5078414180 @default.
- W2000231382 creator A5084777052 @default.
- W2000231382 date "1987-01-01" @default.
- W2000231382 modified "2023-10-17" @default.
- W2000231382 title "A high phosphate diet lowers blood pressure in spontaneously hypertensive rats." @default.
- W2000231382 cites W1978243900 @default.
- W2000231382 cites W1979845477 @default.
- W2000231382 cites W1993040817 @default.
- W2000231382 cites W2005385634 @default.
- W2000231382 cites W2018416184 @default.
- W2000231382 cites W2021820319 @default.
- W2000231382 cites W2040306557 @default.
- W2000231382 cites W2040983621 @default.
- W2000231382 cites W2070985645 @default.
- W2000231382 cites W2076871833 @default.
- W2000231382 cites W2080152720 @default.
- W2000231382 cites W2090942068 @default.
- W2000231382 cites W2091829139 @default.
- W2000231382 cites W2101206284 @default.
- W2000231382 cites W2126470866 @default.
- W2000231382 doi "https://doi.org/10.1161/01.hyp.9.1.96" @default.
- W2000231382 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3793204" @default.
- W2000231382 hasPublicationYear "1987" @default.
- W2000231382 type Work @default.
- W2000231382 sameAs 2000231382 @default.
- W2000231382 citedByCount "26" @default.
- W2000231382 countsByYear W20002313822017 @default.
- W2000231382 countsByYear W20002313822018 @default.
- W2000231382 crossrefType "journal-article" @default.
- W2000231382 hasAuthorship W2000231382A5009397682 @default.
- W2000231382 hasAuthorship W2000231382A5033276783 @default.
- W2000231382 hasAuthorship W2000231382A5078414180 @default.
- W2000231382 hasAuthorship W2000231382A5084777052 @default.
- W2000231382 hasBestOaLocation W20002313821 @default.
- W2000231382 hasConcept C126322002 @default.
- W2000231382 hasConcept C134018914 @default.
- W2000231382 hasConcept C185592680 @default.
- W2000231382 hasConcept C2777132085 @default.
- W2000231382 hasConcept C2778573388 @default.
- W2000231382 hasConcept C2992907065 @default.
- W2000231382 hasConcept C55493867 @default.
- W2000231382 hasConcept C71924100 @default.
- W2000231382 hasConcept C84393581 @default.
- W2000231382 hasConceptScore W2000231382C126322002 @default.
- W2000231382 hasConceptScore W2000231382C134018914 @default.
- W2000231382 hasConceptScore W2000231382C185592680 @default.
- W2000231382 hasConceptScore W2000231382C2777132085 @default.
- W2000231382 hasConceptScore W2000231382C2778573388 @default.
- W2000231382 hasConceptScore W2000231382C2992907065 @default.
- W2000231382 hasConceptScore W2000231382C55493867 @default.
- W2000231382 hasConceptScore W2000231382C71924100 @default.
- W2000231382 hasConceptScore W2000231382C84393581 @default.
- W2000231382 hasIssue "1" @default.
- W2000231382 hasLocation W20002313821 @default.
- W2000231382 hasLocation W20002313822 @default.
- W2000231382 hasLocation W20002313823 @default.
- W2000231382 hasOpenAccess W2000231382 @default.
- W2000231382 hasPrimaryLocation W20002313821 @default.
- W2000231382 hasRelatedWork W1693950885 @default.
- W2000231382 hasRelatedWork W1966464627 @default.
- W2000231382 hasRelatedWork W2105612511 @default.
- W2000231382 hasRelatedWork W2125128110 @default.
- W2000231382 hasRelatedWork W2129462573 @default.
- W2000231382 hasRelatedWork W2130523537 @default.
- W2000231382 hasRelatedWork W2164287263 @default.
- W2000231382 hasRelatedWork W2414806821 @default.
- W2000231382 hasRelatedWork W2748952813 @default.
- W2000231382 hasRelatedWork W4229718260 @default.
- W2000231382 hasVolume "9" @default.
- W2000231382 isParatext "false" @default.
- W2000231382 isRetracted "false" @default.
- W2000231382 magId "2000231382" @default.
- W2000231382 workType "article" @default.