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- W2000232433 abstract "Cucurbit[n]urils (CB[n]; n = 5, 6, 7, 8 or 10) are a family of macrocycles made from the acid-catalyzed condensation of glycoluril and formaldehyde.The synthesis of CB[n] using microwave radiation has been examined and the effect of acid type, reaction time and temperature on the distribution of products has been determined. Synthesis in HCl yields CB[5], CB[6], CB[7] and CB[8] in 10 min and is most efficient at 160 °C. Synthesis in H(2)SO(4) yields mostly CB[6] in 3 min and is most efficient at 160 °C.Microwave synthesis provides an efficient and cost-effective method for the large-scale production of CB[n] for a range of applications, particularly drug delivery." @default.
- W2000232433 created "2016-06-24" @default.
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- W2000232433 date "2010-02-01" @default.
- W2000232433 modified "2023-09-24" @default.
- W2000232433 title "Microwave synthesis of cucurbit[<i>n</i>]urils" @default.
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- W2000232433 doi "https://doi.org/10.4155/fmc.09.118" @default.
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