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• W2000232566 abstract "Purpose: To develop a functional MRI method for producing eye dominance histograms in humans at 1.5 Tesla (T). Methods: In the first set of experiments, 8 normal persons were tested. The eye dominance of each voxel within the person's visually activated primary visual cortex was determined with Student t statistics during a left eye versus right eye contrast. Eye dominance distribution was plotted, and the mean t statistic was used to describe the histogram asymmetry. In the second set of experiments, the effect of monocular optical blur and decreased luminance via filter was studied, and eye dominance distributions were similarly determined. Results: The eye dominance histogram in each of the 8 normals was approximately symmetric; the average mean t value was +0.13. All 4 subjects with the right eye blurred had histograms approximately symmetric or slightly shifted toward the left eye (average mean t = +0.56), and all 4 subjects with the right eye filtered had histograms dramatically shifted toward the left eye (average mean t = +2.22). The average mean t for the group with the right eye filtered was significantly different from that of the other 2 groups (P < .0001). Conclusions: With noninvasive methods in normal persons, functional magnetic resonance imaging techniques at 1.5 T were able to characterize the distribution of eye dominance of voxels in primary visual cortex, based upon their t statistic in the left eye versus right eye contrast. The method is sensitive to filtering but relatively insensitive to visual blur. This approach may have a future use in the study of amblyopia in humans.(J AAPOS 2002;6:40-8)" @default.
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• W2000232566 date "2002-02-01" @default.
• W2000232566 modified "2023-10-18" @default.
• W2000232566 title "Eye dominance in the visual cortex using functional MRI at 1.5 T: An alternative method" @default.
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• W2000232566 doi "https://doi.org/10.1067/mpa.2002.120170" @default.
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