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- W2000235556 abstract "Abstract Guanosine 3′,5′-phosphoric acid alkyl esters were synthesized by reaction of the free acid of guanosine 3′,5′-phosphate (cGMP) with the appropriate diazoalkane. The resulting pair of diastereoisomers was separated chromatographically, and the conformations were assigned on the basis of 31 P-nmr. Hydrolysis of the compounds in water was measured, and their half-lives were determined. The ability of the compounds to act as substrates for phosphodiesterase from beef heart was tested, and their inhibition of this enzyme was measured." @default.
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- W2000235556 date "1979-03-01" @default.
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- W2000235556 title "Synthesis and reactivity of guanosine 3′,5′-phosphoric acid alkyl esters" @default.
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- W2000235556 doi "https://doi.org/10.1016/0045-2068(79)90031-2" @default.
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